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Pre-Analytical Workstations: A Tool for Reducing Laboratory Errors
Pre-Analytical Workstations as a Tool for Reducing Laboratory ErrorsReducing errors and improving quality are an integral part of Laboratory Medicine. Laboratory testing, a highly complex process commonly called the total testing process (TTP), is usually subdivided into three traditional (pre-, intra-, and post-) analytical phases.
Giorgio Da Rin
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The International Organization for Standardization (ISO) 15189:2012 standard aims to improve quality in medical laboratories through standardization of all key elements in the total testing process, including the pre-analytical phase.
Pieter Vermeersch +2 more
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Pre-Analytical Variables in miRNA Analysis
Clinical Biochemistry, 2013MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the regulation of cellular processes and have been shown to be differentially expressed in neoplasia and other disease states. This renders miRNAs promising diagnostic and prognostic biomarkers in tissues and body fluids, especially in blood. However, numerous variables can influence the
Christina M. Lockwood, Nils Becker
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Pre‐Analytical Factors and Measurement Uncertainty
Scandinavian Journal of Clinical and Laboratory Investigation, 2005Pre-analytical factors are an important source of variation or errors in clinical laboratory measurements. Based on the new accreditation standards, medical and laboratory professions now seek to develop tools to deal systematically with these diverse factors. Several obvious pre-analytical uncertainty components were estimated in pragmatic experiments
P Koskinen
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Management of pre-analytical nonconformities
Annales de biologie clinique, 2010The main nonconformities enumerated to facilitate consensual codification. In each case, an action is defined: refusal to realize the examination with request of a new sample, request of information or correction, results cancellation, nurse or physician information. A traceability of the curative, corrective and preventive actions is needed.
Z, Berkane +7 more
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Pre-Analytical Issues for Testosterone and Estradiol Assays
Steroids, 2008In order to standardize and harmonize testosterone measurement, it is vital to identify and minimize pre-analytical error as well as standardize them when developing reference intervals. These pre-analytic issues can be separated into technical and biological factors. Technical factors to address are the type of sample (serum vs.
Hershel Raff, Patrick M Sluss
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The Pre-analytical Phase in Surgical Pathology
2015Several sequential passages are involved in the pre-analytical handling of surgical specimens from resection in the surgical theater to paraffin-embedding and storage. Each passage is highly critical and can significantly affect the preservation of morphology, antigens, and nucleic acids.
Gianni, Bussolati +2 more
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Pre‐analytical and analytical variability of reticulocyte counts in dogs
Veterinary Record, 2023ABSTRACT Background Automated fluorescence‐based haematology analysers are now available for reticulocyte enumeration in veterinary medicine, but manual counting is still largely used. This study aimed to evaluate potential sources of analytical and pre‐analytical errors when performing ...
Roberta Franchi +5 more
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Pre-Analytical Variation of Some Haematological Quantities
Clinical Chemistry and Laboratory Medicine, 2008It is customary to assume that pre-analytical variation is negligible if all pre-analytical sources of variation have been standardised. The aim of this study was to quantify the pre-analytical variation of some haematological quantities frequently measured in clinical laboratories.The experimental design considers different sources of pre-analytical ...
Ariadna Padró-Miquel +2 more
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