Results 201 to 210 of about 420,702 (297)

Pre-analytical errors during HIV viral load (HIV-VL) and early infant diagnosis (EID) testing in Cameroon. [PDF]

PLoS One
Atsama-Amougou M, Atsinkou SN, Bouba Y, Amadou H, Ngo-Malabo TE, Fainguem NN, Nwobegahay J, Vuchas C, Elise E, Bille BE, Nguiala DD, Biongolo E, Lamare BN, Liman Y, Tongo M, Mpabuka E, Ayouba A, Kouanfack C, Meka AFZ, Fokam J.   +19 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Probable European-profile <i>Borrelia</i>-associated myocarditis in an Australian patient with immune resolution following early therapy: a case report. [PDF]

Front Med (Lausanne)
Mitsakos K, Heuer PE, Beninati T, Polley DJ, Schloeffel RJ, Hudson BJ.   +5 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Integrating narrative medicine into laboratory quality improvement: a sustainable model for reducing coagulation specimen rejections. [PDF]

Implement Sci Commun
Huang Y, Chen Z, Liu Q, Deng H, Hu Y.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Development and validation of an LC-MS/MS assay for the quantification of Miransertib in human plasma and clinical application. [PDF]

J Chromatogr B Analyt Technol Biomed Life Sci
Khan RMN, Arisa OT, Zeng Y, Rostagni O, Redick C, Paris KM, Biesecker LG, Ours CA, Figg WD.   +8 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

A Critical Review of Children in Rural Latin America: Toward Meaningful Engagement in Complex Research Contexts. [PDF]

Behav Sci (Basel)
Mazó J, Jiménez-Sánchez C, Loots G, Losantos M.   +3 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source