Results 241 to 250 of about 3,757,704 (310)

Women with a history of gestational diabetes mellitus have preserved sensory nerve‐mediated dilatation in the cutaneous microvasculature

Experimental Physiology, EarlyView.
Abstract Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)‐dependent mechanisms, persists after GDM.
Grace S. Maurer, Kelsey S. Schwartz, Diana I. Jalal, Anna E. Stanhewicz   +3 more
wiley   +1 more source

Diagnostic performance of urinary adipsin as a screening biomarker for pre-eclampsia. [PDF]

Int J Gynaecol Obstet
Opoku Mensah B, Anim E, Ahenkorah Fondjo L, Gyan B, Dapare PPM.   +4 more
europepmc   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Knowledge, practice patterns, and guideline implementation for pre-eclampsia risk management among obstetricians in China: an exploratory cross-sectional survey. [PDF]

Front Public Health
Diao S, Wei Y, Feng Y, Yang J, Liu D, Jiao X, Zeng L, Zhou R, Zhang L.   +8 more
europepmc   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

Pre-Eclampsia Among Pregnant Women in Ghana: A Systematic Review & Meta-Analysis of the Current Prevalence, Risk Factors, and Perinatal Outcomes. [PDF]

Health Sci Rep
Boafo EA, Amponsah RD, Atiase Y, Opare-Agyekum D, Obeng GA, Amankwa M.   +5 more
europepmc   +1 more source

High‐elevation adaptation and gestational hypoxia jointly shape vascular development in a rodent placenta

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman, Zachary A. Cheviron, Jeffrey M. Good, Kai Gurnoe‐Brantley, Kylie E. Jewett, Katherine Kiel, Ashley M. Larson   +6 more
wiley   +1 more source

Centralised Identification of Early-Gestation Biospecimens to Support Early-Onset Pre-Eclampsia Prediction. [PDF]

BJOG
Philip CE, Faysal H, Quinney SK, Feng S, Haas DM.   +4 more
europepmc   +1 more source

Understanding pre-eclampsia and fetal growth restriction at high altitude: A narrative review. [PDF]

Int J Gynaecol Obstet
Rangel VS, Castillo JM, Duarte JD, Barreto MA, Ramirez AV, Daza JA, Ruiz-Sternberg ÁM.   +6 more
europepmc   +1 more source

Socioeconomic deprivation and risk of early-onset pre-eclampsia in England: a national population-based cohort study

Phillips E, Caretta Cortegiani F, Aiken C, Knight M, Kajaria-Montag H, Orfanoudaki A, Zhong Y.   +6 more
europepmc   +1 more source