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Obstetric Medicine, 2021
Pre-eclampsia is a leading cause of neonatal and maternal mortality and morbidity that complicates approximately 2–8% of all pregnancies worldwide. The precise cause of pre-eclampsia is not completely understood, with several environmental, genetic, and maternal factors involved in its pathogenesis and pathophysiology.
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Pre-eclampsia is a leading cause of neonatal and maternal mortality and morbidity that complicates approximately 2–8% of all pregnancies worldwide. The precise cause of pre-eclampsia is not completely understood, with several environmental, genetic, and maternal factors involved in its pathogenesis and pathophysiology.
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Family history of pre‐eclampsia as a predictor for pre‐eclampsia in primigravidas
International Journal of Gynecology & Obstetrics, 1998Abstract Objective: To assess the clinical utility of knowledge of a family history of pre‐eclampsia as a predictor for the development of pre‐eclampsia in primigravid women. Methods: 368 primigravid women were prospectively recruited from the outpatients department of an obstetric teaching ...
Cincotta, RB, Brennecke, SP
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The Lancet
Pre-eclampsia is a multisystem disorder that arises in at least 2-4% of pregnancies and is characterised by hypertension and new-onset organ dysfunction. The pathophysiology of pre-eclampsia is diverse but mostly involves a mismatch between fetoplacental demands and uteroplacental supply, combined with a maternal predisposition to cardiometabolic ...
Mark C Walker +16 more
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Pre-eclampsia is a multisystem disorder that arises in at least 2-4% of pregnancies and is characterised by hypertension and new-onset organ dysfunction. The pathophysiology of pre-eclampsia is diverse but mostly involves a mismatch between fetoplacental demands and uteroplacental supply, combined with a maternal predisposition to cardiometabolic ...
Mark C Walker +16 more
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The Lancet, 1978
Abstract Immunological tests (lymphocyte response to phytohaemagglutinin, HLA antibody production, mixed lymphocyte reaction, HLA types and degree of matching) in women with severe pre-eclampsia show that their immunological activity is reduced or suggest that there is a high degree of immunological compatibility between mother and child.
J S, Scott, D M, Jenkins, J A, Need
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Abstract Immunological tests (lymphocyte response to phytohaemagglutinin, HLA antibody production, mixed lymphocyte reaction, HLA types and degree of matching) in women with severe pre-eclampsia show that their immunological activity is reduced or suggest that there is a high degree of immunological compatibility between mother and child.
J S, Scott, D M, Jenkins, J A, Need
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BJOG: An International Journal of Obstetrics & Gynaecology, 1973
SummaryThe urine/serum ratios of seven proteins of varying molecular weight have been determined in patients with pre‐eclampsia, using radial immunodiffusion. A linear excretion pattern of protein clearance on molecular weight has been confirmed in pregnancy proteinuria. Protein selectivity indices, based on this relationship have been derived for each
M D, Simanowitz +2 more
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SummaryThe urine/serum ratios of seven proteins of varying molecular weight have been determined in patients with pre‐eclampsia, using radial immunodiffusion. A linear excretion pattern of protein clearance on molecular weight has been confirmed in pregnancy proteinuria. Protein selectivity indices, based on this relationship have been derived for each
M D, Simanowitz +2 more
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Seminars in Perinatology, 2009
Pre-eclampsia is a multisystem disorder that is unique to pregnancy, affecting at least 5% of all gravidas. The mainstay of this diagnosis is a combination of new-onset hypertension and proteinuria. The kidney deserves particular attention because of the physiologic as well as pathologic changes that can affect this vital organ in pregnancy.
Fadi G, Mirza, Kirsten Lawrence, Cleary
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Pre-eclampsia is a multisystem disorder that is unique to pregnancy, affecting at least 5% of all gravidas. The mainstay of this diagnosis is a combination of new-onset hypertension and proteinuria. The kidney deserves particular attention because of the physiologic as well as pathologic changes that can affect this vital organ in pregnancy.
Fadi G, Mirza, Kirsten Lawrence, Cleary
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The Lancet, 2000
Pre-eclampsia is associated with significant morbidity and mortality for mother and baby, but it resolves completely post partum. Despite a steady reduction in maternal mortality from the disorder in more developed countries, it remains one of the most common reasons for a woman to die during pregnancy.
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Pre-eclampsia is associated with significant morbidity and mortality for mother and baby, but it resolves completely post partum. Despite a steady reduction in maternal mortality from the disorder in more developed countries, it remains one of the most common reasons for a woman to die during pregnancy.
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The Lancet, 1996
In developed countries preeclampsia is the leading cause of maternal mortality and a major factor in perinatal mortality. The ability to predict clinical preeclampsia would enable increased surveillance of high-risk pregnant women and treatment in the early stages before preeclampsia leads to irreversible pathophysiological changes.
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In developed countries preeclampsia is the leading cause of maternal mortality and a major factor in perinatal mortality. The ability to predict clinical preeclampsia would enable increased surveillance of high-risk pregnant women and treatment in the early stages before preeclampsia leads to irreversible pathophysiological changes.
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Hemoconcentration and pre-eclampsia
Archives of Gynecology, 1981We measured erythrocyte aggregation and hematocrit in 155 uncomplicated pregnancies and in 55 pregnant women with pre-eclampsia. In the later group we found increased erythrocyte aggregation and a higher hematocrit than in normal patients of comparable gestational age. Erythrocyte aggregation correlated well with plasma fibrinogen levels (r = 0.74) but
L, Heilmann +3 more
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Seminars in Thrombosis and Hemostasis, 2011
Pre-eclampsia (P-EC) is a multisystem disorder exclusive to pregnancy. It complicates ~2 to 8% of all pregnancies and remains a major cause of maternal mortality. P-EC is characterized by a profound hypercoagulable state. The delicate hemostatic balance that must be maintained in the uteroplacental circulation during pregnancy makes this system ...
Ismail, Siti Khadijah, Higgins, John R
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Pre-eclampsia (P-EC) is a multisystem disorder exclusive to pregnancy. It complicates ~2 to 8% of all pregnancies and remains a major cause of maternal mortality. P-EC is characterized by a profound hypercoagulable state. The delicate hemostatic balance that must be maintained in the uteroplacental circulation during pregnancy makes this system ...
Ismail, Siti Khadijah, Higgins, John R
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