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Lancet, The, 2010
Pre-eclampsia remains a leading cause of maternal and perinatal mortality and morbidity. It is a pregnancy-specific disease characterised by de-novo development of concurrent hypertension and proteinuria, sometimes progressing into a multiorgan cluster of varying clinical features.
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Pre-eclampsia remains a leading cause of maternal and perinatal mortality and morbidity. It is a pregnancy-specific disease characterised by de-novo development of concurrent hypertension and proteinuria, sometimes progressing into a multiorgan cluster of varying clinical features.
+2 more
exaly +4 more sources
Family history of pre‐eclampsia as a predictor for pre‐eclampsia in primigravidas
International Journal of Gynecology and Obstetrics, 1998AbstractObjective: To assess the clinical utility of knowledge of a family history of pre‐eclampsia as a predictor for the development of pre‐eclampsia in primigravid women. Methods: 368 primigravid women were prospectively recruited from the outpatients department of an obstetric teaching hospital.
Shaun Brennecke
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The Lancet, 2005
Pre-eclampsia is a major cause of maternal mortality (15-20% in developed countries) and morbidities (acute and long-term), perinatal deaths, preterm birth, and intrauterine growth restriction. Key findings support a causal or pathogenetic model of superficial placentation driven by immune maladaptation, with subsequently reduced concentrations of ...
Sibai, B., Dekker, G., Kupferminc, M.
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Pre-eclampsia is a major cause of maternal mortality (15-20% in developed countries) and morbidities (acute and long-term), perinatal deaths, preterm birth, and intrauterine growth restriction. Key findings support a causal or pathogenetic model of superficial placentation driven by immune maladaptation, with subsequently reduced concentrations of ...
Sibai, B., Dekker, G., Kupferminc, M.
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Obstetrical & Gynecological Survey, 1979
Summary: In a series of 26,209 patients, the incidence of pre‐eclampsia was 9.3%, being significantly higher in primiparae (14.1%) than multiparae (5.7%) (P<0.001). In patients with early‐onset pre‐eclampsia there were highly significant (P<0.001) increases in the incidences of proteinuria, severe hypertension, placental abruption, fetal growth ...
P A, Long, D A, Abell, N A, Beischer
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Summary: In a series of 26,209 patients, the incidence of pre‐eclampsia was 9.3%, being significantly higher in primiparae (14.1%) than multiparae (5.7%) (P<0.001). In patients with early‐onset pre‐eclampsia there were highly significant (P<0.001) increases in the incidences of proteinuria, severe hypertension, placental abruption, fetal growth ...
P A, Long, D A, Abell, N A, Beischer
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Obstetric Medicine, 2021
Pre-eclampsia is a leading cause of neonatal and maternal mortality and morbidity that complicates approximately 2–8% of all pregnancies worldwide. The precise cause of pre-eclampsia is not completely understood, with several environmental, genetic, and maternal factors involved in its pathogenesis and pathophysiology.
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Pre-eclampsia is a leading cause of neonatal and maternal mortality and morbidity that complicates approximately 2–8% of all pregnancies worldwide. The precise cause of pre-eclampsia is not completely understood, with several environmental, genetic, and maternal factors involved in its pathogenesis and pathophysiology.
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The Lancet, 1978
Abstract Immunological tests (lymphocyte response to phytohaemagglutinin, HLA antibody production, mixed lymphocyte reaction, HLA types and degree of matching) in women with severe pre-eclampsia show that their immunological activity is reduced or suggest that there is a high degree of immunological compatibility between mother and child.
J S, Scott, D M, Jenkins, J A, Need
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Abstract Immunological tests (lymphocyte response to phytohaemagglutinin, HLA antibody production, mixed lymphocyte reaction, HLA types and degree of matching) in women with severe pre-eclampsia show that their immunological activity is reduced or suggest that there is a high degree of immunological compatibility between mother and child.
J S, Scott, D M, Jenkins, J A, Need
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BJOG: An International Journal of Obstetrics & Gynaecology, 1973
SummaryThe urine/serum ratios of seven proteins of varying molecular weight have been determined in patients with pre‐eclampsia, using radial immunodiffusion. A linear excretion pattern of protein clearance on molecular weight has been confirmed in pregnancy proteinuria. Protein selectivity indices, based on this relationship have been derived for each
M D, Simanowitz +2 more
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SummaryThe urine/serum ratios of seven proteins of varying molecular weight have been determined in patients with pre‐eclampsia, using radial immunodiffusion. A linear excretion pattern of protein clearance on molecular weight has been confirmed in pregnancy proteinuria. Protein selectivity indices, based on this relationship have been derived for each
M D, Simanowitz +2 more
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Seminars in Perinatology, 2009
Pre-eclampsia is a multisystem disorder that is unique to pregnancy, affecting at least 5% of all gravidas. The mainstay of this diagnosis is a combination of new-onset hypertension and proteinuria. The kidney deserves particular attention because of the physiologic as well as pathologic changes that can affect this vital organ in pregnancy.
Fadi G, Mirza, Kirsten Lawrence, Cleary
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Pre-eclampsia is a multisystem disorder that is unique to pregnancy, affecting at least 5% of all gravidas. The mainstay of this diagnosis is a combination of new-onset hypertension and proteinuria. The kidney deserves particular attention because of the physiologic as well as pathologic changes that can affect this vital organ in pregnancy.
Fadi G, Mirza, Kirsten Lawrence, Cleary
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The Lancet, 2000
Pre-eclampsia is associated with significant morbidity and mortality for mother and baby, but it resolves completely post partum. Despite a steady reduction in maternal mortality from the disorder in more developed countries, it remains one of the most common reasons for a woman to die during pregnancy.
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Pre-eclampsia is associated with significant morbidity and mortality for mother and baby, but it resolves completely post partum. Despite a steady reduction in maternal mortality from the disorder in more developed countries, it remains one of the most common reasons for a woman to die during pregnancy.
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The Lancet, 1996
In developed countries preeclampsia is the leading cause of maternal mortality and a major factor in perinatal mortality. The ability to predict clinical preeclampsia would enable increased surveillance of high-risk pregnant women and treatment in the early stages before preeclampsia leads to irreversible pathophysiological changes.
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In developed countries preeclampsia is the leading cause of maternal mortality and a major factor in perinatal mortality. The ability to predict clinical preeclampsia would enable increased surveillance of high-risk pregnant women and treatment in the early stages before preeclampsia leads to irreversible pathophysiological changes.
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