Results 101 to 110 of about 293,582 (300)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Coxsackievirus A6 U.K. Genetic and Clinical Epidemiology Pre- and Post-SARS-CoV-2 Emergence

Pathogens
Coxsackievirus A6 (CVA6) has become increasingly clinically relevant as a cause of Hand, Foot and Mouth Disease (HFMD) globally since 2008. However, most laboratories do not routinely determine the enteroviral type of positive samples.
Alice M. Joyce, Jack D. Hill, Theocharis Tsoleridis, Stuart Astbury, Louise Berry, Hannah C. Howson-Wells, Nancy Allen, Ben Canning, Carl B. Jones, Gemma Clark, William L. Irving, Alexander W. Tarr, C. Patrick McClure   +12 more
doaj   +1 more source

Economic Aspects of Physical Intra-Row Weed Control in Seeded Onions [PDF]

, 1998
The paper presents a model to calculate the costs for weed control in organic row crops. The model makes it possible to analyse the economic consequences of different weed control strategies in row crops. Particularly the time needed for hand-weeding had
Melander, Senior scientist Bo
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Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Guidelines for physical weed control research: flame weeding, weed harrowing and intra-row cultivation [PDF]

, 2004
A prerequisite for good research is the use of appropriate methodology. In order to aggregate sound research methodology, this paper presents some tentative guidelines for physical weed control research in general, and flame weeding, weed harrowing and ...
Ascard, J., Bertram, A., Cloutier, D.C., Kurstjens, D., Mead, A., Raffaelli, M., Rasmussen, Jesper, Vanhala, P.   +7 more
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Behaviour of pre-emergence herbicides in poplar nurseries

Forest Systems, 2002
The poplar cutting response to five pre-emergence herbicides (Oxadiazon, Isoxaben, Oxifluorfen, Tiazopir and Pendimetaline) in nursery conditions were studied. In order to evaluate quantitatively the selectivity and efficacy of the herbicides, the shoot height of the trees and the dry weight of the weeds were recorded. Species were identified and their
Sixto, H., Grau, J. M., García Baudin, J. M.   +2 more
openaire   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

State-Contingent Demand for Herbicide-Tolerance Seed Trait [PDF]

Suppose a farmer had to apply a herbicide pre-emergence or not at all. The advent of a herbicide-tolerance trait innovation then provides the option to wait for more information before making a state-contingent post-emergence application.
Hennessy, David A., Saak, Alexander
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Sowing time, false seedbed, row distance and mechanical weed control in organic winter wheat. [PDF]

, 2000
In organic farming, mechanical weed control in winter wheat is often difficult to carry out in the fall, and may damage the crop, and weed harrowing in the spring is not effective against erect, tap-rooted weeds such as Tripleurospermum inodorum, Papaver
Rasmussen, Ilse A.
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