Results 131 to 140 of about 65,616 (255)

Campus healthcare workers' knowledge and views on injectable pre-exposure prophylaxis prior to rollout in South Africa: A qualitative study. [PDF]

PLOS Glob Public Health
Mbatha NN, Mpofana N, Gumede D.
europepmc   +1 more source

Can't outrun recurrence: Long‐term outcomes of treating American black bear sarcoptic mange

The Journal of Wildlife Management, EarlyView.
Abstract The growing incidence of sarcoptic mange in American black bears (Ursus americanus) has become a concern for wildlife managers in the eastern United States. Inconsistency in the use of single and multi‐dose treatment approaches makes it difficult to evaluate their effects on post‐release outcomes of mange‐rehabilitated bears, which remain ...
Raquel Francisco, Viviana Berdecia‐Martinez, Marcelo Jorge, Jillian R. Broadhurst, Katherine Martin, Carl Tugend, John Tracey, Karra Pierce, Peach Van Wick, Michael J. Yabsley   +9 more
wiley   +1 more source

Seminal plasma concentrations of long-acting cabotegravir in men receiving HIV pre-exposure prophylaxis. [PDF]

Antimicrob Agents Chemother
Moschese D, Fusetti C, Lazzarin S, Giacomelli A, Mazzotta V, Cattaneo D, D'Avolio A, Caruso F, Maddalena D, Petri F, Antinori A, Gervasoni C, Gori A, Cossu MV.   +13 more
europepmc   +1 more source

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui, Yu‐Shi He, Xuan‐Hui Wang, Cheng Li, Gang Wang, Ming Chen, Shu‐Min Chen   +6 more
wiley   +1 more source

Drivers of Vertical HIV Transmission in Sub-Saharan Africa and the Impact and Cost-Effectiveness of Targeted and Universal Lenacapavir Pre-Exposure Prophylaxis. [PDF]

J Int AIDS Soc
Yakusik A, Walters MK, Mattur D, Brar S, Johnson LF, Meyer-Rath G, Jamieson L, Mushavi A, Stover J, Mahy M.   +9 more
europepmc   +1 more source

Sport participation after isolated distal femoral osteotomy in young patients: High return‐to‐sport rates and predictive role of preoperative activity level

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The present study aimed to assess return to sport (RTS) rate, activity level and return to work (RTW) in young, physically active patients who underwent isolated distal femoral osteotomy (DFO) for lateral knee pain and valgus malalignment.
Gian Andrea Lucidi, Federico Maria Adravanti, Claudio Rossi, Margherita Bonaiuti, Stefano Di Paolo, Alberto Grassi, Stefano Zaffagnini   +6 more
wiley   +1 more source

Pharmacological markers of HIV prevention for oral pre-exposure prophylaxis in men who have sex with men. [PDF]

Nat Commun
Iannuzzi S, Müller M, Yu Y, Zhang L, Hendrix CW, Bies RR, von Kleist M.   +6 more
europepmc   +1 more source

Four general‐purpose large language models (ChatGPT‐5, Claude 4, Grok 4 and Gemini 2.5) show comparable performance in specialised total knee arthroplasty clinical questions

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate and compare the performance of four general‐purpose large language models (LLMs) (ChatGPT‐5, Claude 4, Grok 4 and Gemini 2.5) in answering specialised clinical questions related to total knee arthroplasty (TKA) derived from the World Expert Meeting in Arthroplasty (WEMA). Methods This is a cross‐sectional comparative study.
Oriol Pujol, Robert Ferrer, Alex Coelho, Felix C. Oettl, Balint Zsidai, Joan Leal‐Blanquet, Michael T. Hirschmann, Kristian Samuelsson   +7 more
wiley   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source