Results 111 to 120 of about 6,517,332 (327)

The Thermal Infrared Sensor (TIRS) on Landsat 8: Design Overview and Pre-Launch Characterization

Remote Sensing, 2015
The Thermal Infrared Sensor (TIRS) on Landsat 8 is the latest thermal sensor in that series of missions. Unlike the previous single-channel sensors, TIRS uses two channels to cover the 10–12.5 micron band.
D. Reuter, Cathleen M. Richardson, F. Pellerano, J. Irons, R. Allen, Martha C. Anderson, M. Jhabvala, A. Lunsford, M. Montanaro, Ramsey L. Smith, Z. Tesfaye, K. Thome   +11 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

System and Method for Air Launch from a Towed Aircraft

, 2018
The invention is a system and method of air launching a powered launch vehicle into space or high altitude. More specifically, the invention is a tow aircraft which tows an unpowered glider, with the powered launch vehicle attached thereto, to launch ...
Budd, Gerald D
core  

Thermodynamic Modeling and Parameter Study of a Supercritical CO₂ Pneumatic Launch System for Sustainable High-Payload Applications

Energies
This study develops and validates a thermodynamic model for a supercritical carbon dioxide (CO2) pneumatic launch system, evaluating its potential as an environmentally friendly and efficient energy conversion technology alternative to conventional ...
Gaoliang Liao, Zhong Liu, Feng Zhang, Jiaqiang E   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Pre-launch calibration of the HIRDLS instrument

Report about the aims for the calibration of the HIRDLS instrument.
Barnett, JJ, Darbyshire, AG, Hepplewhite, CL, Palmer, CWP, Row, F, Venters, P, Watkins, REJ, Whitney, JG, Gille, JC, Johnson, BR   +9 more
openaire   +2 more sources

ASTP Astronauts Pre-launch Breakfast

, 1975
For Release: July 15, 1975 Photo No. 75-H-760 108-KSC-75P-383 KENNEDY SPACE CENTER, FLA. – ASTP crewmen (left to right) Donald Slayton, Thomas Stafford, and Vance Brand enjoy a pre-launch breakfast in the crew quarters of the KSC’s Manned Spacecraft ...
Southwestern Oklahoma State University, NASA   +1 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source