Results 141 to 150 of about 241,576 (378)

Lithium and chromospherically active single giants [PDF]

Nine chromospherically active single K giants were identified from surveys of chromospherically active stars. The stars have v sin i's ranging from 6 to 46 km/sec.
Fekel, Francis C.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

New proper motions of pre-main sequence stars in Taurus-Auriga [PDF]

, 1997
S. Frink, S. Roêser, R. Neuhäeuser, M. Sterzik   +3 more
openalex   +1 more source

Discovery of magnetic fields in the very young, massive stars W601 (NGC 6611) and OI 201 (NGC 2244)

, 2008
Context: Recent spectropolarimetric observations of Herbig Ae/Be stars have yielded new arguments in favour of a fossil origin for the magnetic fields of intermediate mass stars.
Balog, Belikov, Bohlender, Brown, C. Catala, C. P. Folsom, Catala, Chen, D. Bohlender, de Winter, Donati, Ducati, Dufton, E. Alecian, G. A. Wade, Guarcello, Hensberge, Hubeny, Hubeny, Høg, J. D. Landstreet, J. Grunhut, J.-C. Bouret, J.-F. Donati, Kumar, Landstreet, Morel, Palla, Park, Pérez, S. Bagnulo, T. Boehm, Vrancken, Wade, Wade   +34 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Disk-locking Regulates Stellar Rotation in Young Clusters: Insights from NGC 2264

The Astrophysical Journal
Many young clusters possess extended main sequences, a phenomenon commonly ascribed to stellar rotation. However, the mechanism behind their very wide stellar rotation distributions remains unclear.
Yutian Bu, Chenyu He, Min Fang, Chengyuan Li   +3 more
doaj   +1 more source

Coronal structure geometries on pre-main sequence stars [PDF]

, 2001
F. Favata, G. Micela, F. Reale
openalex   +1 more source