Results 141 to 150 of about 451,529 (372)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Tractability properties of the weighted star discrepancy of the Halton sequence [PDF]

arXiv, 2018
We study the weighted star discrepancy of the Halton sequence. In particular, we show that the Halton sequence achieves strong polynomial tractability for the weighted star discrepancy for product weights $(\gamma_j)_{j \ge 1}$ under the mildest condition on the weight sequence known so far for explicitly constructive sequences. The condition requires $
arxiv  

Low-mass pre--main-sequence stars in the Magellanic Clouds

, 2012
[Abridged] The stellar Initial Mass Function (IMF) suggests that sub-solar stars form in very large numbers. Most attractive places for catching low-mass star formation in the act are young stellar clusters and associations, still (half-)embedded in star-
A. Chieffi, A. Duquennoy, A. Nota, A. Sicilia-Aguilar, A. Stolte, A. Vallenari, A.E. Piskunov, A.L. Kraus, A.Z. Bonanos, B. Brandl, B. Brandl, B. Burningham, B. Merín, B.A. Whitney, B.E. Westerlund, C. Briceño, C. Briceño, C. Lada, C.-H.R. Chen, C.A. Iglesias, C.A. Tout, C.F. Prosser, C.J. Evans, C.J. Evans, C.J. Lada, C.J. Lada, C.J. Lada, D. Gouliermis, D. Marquardt, D.A. Gouliermis, D.A. Gouliermis, D.A. Gouliermis, D.A. Gouliermis, D.A. Gouliermis, Dimitrios A. Gouliermis, E. Hennekemper, E. Mentuch, E. Sabbi, E. Sabbi, E. Sabbi, E. Tognelli, E.E. Salpeter, F. Allard, F. Damiani, F. Palla, F.J. Rogers, F.J. Swenson, G. Baume, G. Chabrier, G. Marchi De, G. Marchi De, G. Marchi De, H. Karttunen, H. Zinnecker, H.B. Throop, I. Appenzeller, I. Baraffe, I. Baraffe, I. Baraffe, I. Hunter, J. Maíz Apellániz, J. Scalo, J. Woitas, J.B. Hutchings, J.H.J. Bruijne de, J.M. Scalo, J.W. Ferguson, K. Levenberg, K.A. Venn, K.D. Gordon, K.G. Henize, L. Girardi, L. Hartmann, L. Hartmann, L. Origlia, L. Siess, L. Siess, L.A. Hillenbrand, L.A. Hillenbrand, L.A. Hillenbrand, L.A. Hillenbrand, L.A. Hillenbrand, L.B.F.M. Waters, L.R. Carlson, L.R. Carlson, L.W. Hartmann, M. Abramowitz, M. Asplund, M. Cignoni, M. Cignoni, M. Cignoni, M. Gennaro, M. Heydari-Malayeri, M. Robberto, M. Romaniello, M. Romaniello, M. Schmalzl, M. Sewiło, M. Sirianni, M.G. Guarcello, M.G. Petr, M.R. Mokiem, M.S. Povich, N. Bastian, N. Calvet, N. Panagia, N. Rio Da, N. Rio Da, N. Rio Da, N.R. Walborn, N.R. Walborn, P. Battinelli, P. Kroupa, P. Kroupa, P. Madau, P. Massey, P. Massey, P. Massey, P.B. Lucke, P.H. Hauschildt, Q. Liu, Q. Liu, R. Castro, R. Kurucz, R. Köhler, R.A. Gruendl, R.D. Jeffries, R.D. Jeffries, R.D. Mathieu, R.E. Luck, R.J. Allison, S. Degl’Innocenti, S. Ragland, S. Schmeja, S. Stanimirović, S. Yi, S.C. Javiel, S.J. Kenyon, S.P. Littlefair, S.W. Stahler, T. Naylor, T. Preibisch, T. Preibisch, T.A. Smecker-Hane, T.P. Robitaille, Th. Preibisch, W. Brandner, W. Brandner, W. Herbst, W. Herbst, W.H. Sherry, X. Pang, Y.C. Pei   +152 more
core   +1 more source

Spatial distribution of pre-main sequence stars in Taurus.

, 1993
We derive characteristic properties of the nonrandom spatial distribution of pre-main-sequence stars in the Taurus-Auriga molecular cloud by applying several different statistical techniques.
M. Gómez, L. Hartmann, S. Kenyon, R. Hewett   +3 more
semanticscholar   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

The initial period function of late-type binary stars and its variation

, 2011
The variation of the period distribution function of late-type binaries is studied. It is shown that the Taurus--Auriga pre-main sequence population and the main sequence G dwarf sample do not stem from the same parent period distribution with better ...
Adams, Brandner, Connelley, Covino, de Zeuw, Duchêne, Duchêne, Duchêne, Duquennoy, Durisen, Fischer, Fisher, Ghez, Goodwin, Hillenbrand, Horton, Kouwenhoven, Kroupa, Kroupa, Kroupa, Kroupa, Kroupa, Kroupa, Kroupa, Köhler, Köhler, Köhler, Leinert, Luhman, M. G. Petr-Gotzens, Makarov, Mathieu, Maury, Mayor, McCaughrean, Moeckel, Nakajima, P. Kroupa, Parker, Perryman, Petr, Preibisch, Prosser, Raghavan, Ratzka, Reipurth, Richichi, Salim, Simon, Simon, Sterzik, Wichmann   +51 more
core   +1 more source

Lithium Depletion in Fully Convective Pre-Main-Sequence Stars [PDF]

, 1996
We present an analytic calculation of the thermonuclear depletion of lithium in contracting, fully convective, pre-main-sequence stars of mass M ≲ 0.5 M☉. Previous numerical work relies on still uncertain physics (atmospheric opacities and convection, in
L. Bildsten, E. Brown, C. Matzner, G. Ushomirsky   +3 more
semanticscholar   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

Molecular Oncology, EarlyView.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch, Sara Sánchez‐Serra, Marta Rosàs‐Lapeña, Nicolás Costa‐Fraga, Judit Besalú‐Velázquez, Janet Illa‐Bernadí, Silvia Mateo‐Lozano, Florencia Cidre‐Aranaz, Thomas G.P. Grünewald, Ángel Díaz‐Lagares, Roser Lopez‐Alemany, Òscar M. Tirado   +11 more
wiley   +1 more source

The Multiplicity of Pre-Main-Sequence Stars in Southern Star-forming Regions

, 1997
High-resolution studies of young stars in the star-forming regions of Taurus and Ophiuchus have revealed a large population of multiple star systems. To test how applicable this earlier result is for other star-forming regions, we have carried out a K ...
A. Ghez, D. W. McCarthy, D. W. McCarthy, J. Patience, Tracy L. Beck, Tracy L. Beck   +5 more
semanticscholar   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source