Results 61 to 70 of about 1,058,557 (263)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Leaf hyperspectral reflectance detects pre‐visual stress to Fusarium wilt in strawberries
Plant Phenome JournalFusarium wilt, caused by Fusarium oxysporum, threatens global food security and high‐value crops like strawberries (Fragaria × ananassa) in California. Traditional detection, reliant on visual symptoms, often comes too late for intervention.
Jessie Au +6 more
doaj +1 more source
Effect of assembly pre-stress on the scratch behavior of polycarbonate [PDF]
Nanotechnology and Precision EngineeringScratch damage can reduce both the aesthetic appearance and structural integrity of polymer surfaces. To optimize and enhance the scratch resistance of polycarbonate, this study investigates the influence of assembly pre-tensile and pre-compressive ...
Qian Cheng +8 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2015 Stress is a major factor in the development of major depressive disorder (MDD), but few studies have assessed individual risk based on pre-stress traits.
Yoshio eIguchi +5 more
doaj +1 more source
Applied Mathematical Modelling, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Akbaro, SURKHAY, Ozturk, A.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Catastrophic failure mechanism of deep roadways and stress gradient control models
Meitan xuebaoNumerous factors influence the deformation and control of roadway surrounding rock, with stress gradient and pre-tension being two key factors. To investigate the intrinsic relationship between stress gradient and pre-tension and determine the optimal ...
Zhijie WEN +6 more
doaj +1 more source