Results 81 to 90 of about 1,058,557 (263)
Ultrasound-Based Fluid-Structure Interaction Modeling of Abdominal Aortic Aneurysms Incorporating Pre-stress. [PDF]
Front Physiol, 2021 Fonken JHC +5 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Effect of Pre-Stress on Laser-Induced Thermoplastic Deformation of Inconel 718 Beams. [PDF]
Materials (Basel), 2021 Widłaszewski J, Nowak Z, Kurp P.
europepmc +1 more source
Interface Waves in Pre-Stressed Incompressible Solids [PDF]
, 2007 We study incremental wave propagation for what is seemingly the simplest boundary value problem, namely that constitued by the plane interface of a semi-infinite solid. With a view to model loaded elastomers and soft tissues, we focus on incompressible solids, subjected to large homogeneous static deformations.
openaire +3 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Dynamic Characteristic Study of Riser with Complex Pre-stress Distribution
Polish Maritime Research, 2019 In this study, the dynamic characteristic problem of riser structure with complex pre-stress distribution is investigated. At first, the differential equation of the riser structure with complex pre-stress distribution is derived.
Chen Luyun, Yi Hong
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Calmly coping: A Motivational Interviewing Via CoActive Life Coaching (MI-VIA-CALC) pilot intervention for university students with perceived levels of high stress [PDF]
International Journal of Evidence Based Coaching and Mentoring, 2016 Stress is a campus problem. This pre-post pilot study assessed the impact of Motivational Interviewing via Co-Active Life Coaching (MI-via-CALC) on the stress management of 30 full-time, English-speaking Canadian undergraduate students, aged 17-24 years.
Rebecca R. Fried, Jennifer D. Irwin
doaj