Results 151 to 160 of about 370 (215)

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

open access: yesEpilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar   +4 more
wiley   +1 more source

Seismic Performance and Vibration‐Based Damage Identification of Two‐Storey Balloon‐Framed CLT Shear Walls

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT While cross‐laminated timber (CLT) is increasingly utilized in lateral force‐resisting systems in mass timber construction, research has predominantly focused on platform‐type construction. Balloon‐type CLT shear wall systems offer distinct structural advantages, notably the elimination of cumulative perpendicular‐to‐grain compression and a ...
Samira Mohammadyzadeh   +3 more
wiley   +1 more source

Energy‐Based Characterisation of Earthquake Damage in Masonry Infills Through Combined In‐Plane and Out‐of‐Plane Experimental Tests

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT The seismic capacity of structural systems/members is usually defined in terms of deformation thresholds. Although this is effective in many circumstances, disregarding cumulative quantities such as hysteretic energy may be ineffective when low‐cycle fatigue is relevant (e.g., long‐duration ground motions, very soft soils, ground‐motion ...
Roberto Gentile   +11 more
wiley   +1 more source

Climate Driven Water Table Changes and Their Influence on Liquefaction Response of Integral Bridges

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Integral abutment bridges (IABs) eliminate bearings and joints but transfer seismic demand directly into the surrounding soil, making their response highly sensitive to groundwater conditions and soil–structure interaction. This study presents a 60 g centrifuge testing programme on single‐span IABs designed to isolate the influence of water ...
Yazan B. Asia, Gopal S. P. Madabhushi
wiley   +1 more source

Surrogate‐Based Time‐Continuous Seismic Fragility Assessment of Corrosion‐Deteriorated Reinforced Concrete Bridges Under Climate Change

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Seismic fragility assessment of reinforced concrete (RC) bridges exposed to corrosive environments must reliably capture time‐dependent deterioration impacts. Climate change compounds this challenge through nonstationary temperature and humidity variations that accelerate bridge corrosion.
Yexiang Yan, Yazhou Xie
wiley   +1 more source

Severe and Enduring Eating Disorders: A Qualitative Study of Patients' Experiences and Perceived Treatment Needs

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Approximately 25% of individuals with eating disorders develop severe and enduring eating disorders (SEEDs); yet effective treatments remain limited. This study explored lived experiences of SEEDs, focussing on past treatments, as well as current needs and hopes. Method Twenty participants with eating disorders of ≥ 7 years and prior
Emilia Kotilahti   +3 more
wiley   +1 more source

Eating Disorder Clinician Views About the Impact of Out‐of‐Home Calorie Labelling on Their Patients: A Qualitative Interview Study

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Accumulating evidence suggests that people with eating disorders experience mainly negative impacts of out‐of‐home calorie labelling. This study explored eating disorder clinician perspectives on how such labels affect individuals with eating disorders, and their views on implementation of this policy.
Abinaya Nadarajah   +9 more
wiley   +1 more source

Mechanisms of Roadway Instability and Coupled Control Technology for Working Face Passing Through Fault Zones

open access: yesEnergy Science &Engineering, EarlyView.
This study mainly explores the instability characteristics of roadways near faults in the working face. Taking the 51104 transportation roadway of the 51104 working face in Shengxin Coal Mine as the main research object, through theoretical analysis, borehole inspection, numerical simulation and on‐site mine pressure observation, the instability ...
Shuaifeng Yin   +4 more
wiley   +1 more source

Techno‐Economic and Quasi‐Dynamic Load Flow Analysis of a Hybrid Renewable Microgrid for Coastal Industrial Loads

open access: yesEnergy Science &Engineering, EarlyView.
A hybrid PV–wind grid‐connected microgrid for Mongla Port is optimized using HOMER Pro and validated via DIgSILENT quasi‐dynamic load flow. The system achieves a low cost of energy (0.0341 USD/kWh), 70.9% renewable penetration, improved voltage stability, and significant emission reduction, demonstrating a reliable and cost‐effective solution for ...
Md. Behesty Hasan Sagor   +6 more
wiley   +1 more source

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