Results 51 to 60 of about 20,977 (265)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Influence of Friction on Pre-Stressing Construction of Suspen-Dome Structures

open access: yesBuildings
Suspension dome structures are widely utilized due to their superior performance compared to conventional structures. The condition of the cables, particularly the forces they experience, is critical for ensuring the safety of the overall structures ...
Miao Liu   +3 more
doaj   +1 more source

Concrete Silos: Failures, Design Issues and Repair/Strengthening Methods

open access: yesApplied Sciences, 2020
The review article investigated failure, design issues, repair and strengthening of reinforced concrete (RC) silos, primarily in agricultural set-ups. The durability of RC structures was influenced by the nature of the bulk solids, materials used in the ...
Chrysanthos Maraveas
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Influence of Failure Probability Due to Parameter and Anchor Variance of a Freeway Dip Slope Slide—A Case Study in Taiwan †

open access: yesEntropy, 2017
The traditional slope stability analysis used the Factor of Safety (FS) from the Limit Equilibrium Theory as the determinant. If the FS was greater than 1, it was considered as “safe” and variables or parameters of uncertainty in the analysis model were ...
Shong-Loong Chen, Chia-Pang Cheng
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Evaluation of the Functional Capacity of the Cylindric Pre-Stressed Tanks

open access: yesBulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2010
This paper approaches the problem of diagnosing the degradation and the safety estate in exploatation of the cylindrical tanks made out of pre-prestressed concrete, affected by execution errors, especially generated by the design non-observance ...
Emilia Neagu   +3 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

THE EXPOSITION OF EFFECTIVE PRE-STRESSING OF REINFORCED CONCRETE STRUCTURES

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2015
A method of estimation of the exposition of effective pre-stressing of reinforced concrete structures that takes the anisotropy, nonlinearity, and non-equilibrium of force resistance of damages into account is presented.
V M Bondarenko
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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