Results 141 to 150 of about 391,018 (258)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

M1 a-tDCS does not acutely enhance motor skill acquisition of a dexterous, timing-based videogame task in adults. [PDF]

Physiol Rep
Blake BO, Burton WP, Duchow EE, McCallion Q, Poston B, Riley ZA.   +5 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Body mass index, prebiotic supplementation during pregnancy and gestational diabetes mellitus risk: an effect modification analysis from a randomised controlled trial. [PDF]

Nutr J
Pretorius RA, Sullivan TR, Walker SVM, Garssen J, Keelan JA, Silva D, Prescott SL, Palmer DJ.   +7 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Exercise evokes retained motor performance without neuroprotection in a mouse model of Parkinson's disease. [PDF]

Front Physiol
Skelton HM, Hyman N, Fernandez AM, Acerbo E, Scott M, Berglund K, Gutekunst CA, Gross RE.   +7 more
europepmc   +1 more source

AXIOLOGICAL DIMENSION OF THE INVESTIGATOR’S ACTIVITY AT THE STAGE OF PRE-TRIAL INVESTIGATION

Kherson State University Herald. Series Legal Sciences, 2019
V.M. Stratonov, M.M. Novikova
openaire   +2 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Evaluating Cordyceps militaris capsules on post-bronchodilator FEV₁ decline in patients with COPD: a study protocol for double-blind, randomized, placebo-controlled trial. [PDF]

Front Pharmacol
Lin S, Liao T, Fan F, Chen Y, Yan Y, Dong H, Zhan S, Zhang Y, Xiao K, Lin L, Wu L.   +10 more
europepmc   +1 more source

DISCLOSING MATERIALS OF PRE-TRIAL INVESTIGATION

Scientific works of National Aviation University. Series: Law Journal "Air and Space Law", 2019
openaire   +1 more source