Results 51 to 60 of about 3,170,606 (305)

Understanding the Relationship between Culturally Engaging Campus Environments and College Students’ Academic Motivation

open access: yesEducation Sciences, 2022
Low rates of college completion are a major national dilemma, and one way in which college campuses can increase degree attainment rates is by fostering higher levels of academic motivation among students.
Samuel D. Museus, Kiana Shiroma
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Establishing and evaluating a distance master of education program [PDF]

open access: yes, 2000
vii, 61 p. ; 29 cm. --The purpose of this project is twofold. First, it was to establish if there was a need for a Master of Education program in School District 59 in British Columbia. If so, then to evaluate the effectiveness of the delivery model of
Cooper, Brett   +1 more
core  

Exploring the Accuracy and Consistency of a School Readiness Assessment Tool for Preschoolers: Reliability, Validity and Measurement Invariance Analysis

open access: yesJournal of Intelligence, 2023
This study focuses on examining the psychometric properties of the DIFER test, a widely used assessment tool for measuring school readiness. DIFER, which stands for Diagnostic Assessment Systems for Development, has gained prominence in Hungary and some ...
Krisztián Józsa   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Effective pre-school, primary and secondary education project (EPPSE 3-14): influences on students' development in Key Stage 3: social-behavioural outcomes in Year 9 [PDF]

open access: yes, 2011
The Effective Pre-school, Primary and Secondary Education Project (EPPSE) has investigated the academic and social-behavioural development of approximately 3,000 children from the age of 3+ years since 1997.
Draghici, D.   +24 more
core  

The Financial-Accounting Audit in Pre-University Educational Institutions in Romania [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
The purpose of the research is to identify the specific elements of the audit carried out in educational institutions in Romania. The objectives of the research are to offer some practical suggestions for carrying out an audit process in the school and
Anișoara – Elena Pavelescu (Belbe)
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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