Results 81 to 90 of about 3,170,606 (305)

Evolution of suspension bridge structural systems, design theories, and shape-finding methods: A literature survey

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online)
Modern suspension bridges exhibit a trend of lighter structures, more diversified structural forms, and longer spans, the latter already exceeding two kilometers.
Wenming Zhang, Genmin Tian, Yupeng Chen
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

An analysis of pre-service teachers' HIV/AIDS knowledge, attitudes and self-efficacy and their HIV/AIDS teaching tasks

open access: yes, 2005
Includes bibliographical references.This dissertation examines the interface between pre-service teachers' HIV/AIDSknowledge, attitudes and self-efficacy, and their intentions to teach HIV/AIDS knowledge, attitudes and self-efficacy. It is located within
Alexander, Joy
core  

Resource fairs for continuing nursing education [PDF]

open access: yes, 2000
viii, 83 leaves ; 29 cm. --The purpose of this project is to evaluate the appropriateness of a resource fair as a method of providing learning opportunities to health care professionals, primarily nurses. Educators in hospitals today are faced with the
University of Lethbridge. Faculty of Education   +1 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Story and stereotype : aboriginal literature as anti-racist education [PDF]

open access: yes, 2004
xviii, 163 leaves ; 28 cm.Textbooks newly approved for use in secondary schools in Alberta reflect the belief that not only does literature have the power to change and shape our thinking, but also that the non-White voices of our culture need to be ...
Gill, Isabel   +1 more
core  

Conceptualising Inclusive Education: Insights from South African Primary School Principals

open access: yesIndonesian Journal on Learning and Advanced Education (IJOLAE)
This study explores the understanding of inclusive education by principals in South African primary schools. It draws on in-depth research and reflective engagements over the past 30 years on the implementation of inclusive education in South African ...
Zakhele Dennis Nzuza   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Weber health education model : health care provider-patient interactions [PDF]

open access: yes, 2004
ix, 128 leaves ; 29 cm. --This qualitative project introduces and explores the creation of a new health education model, which emerged from a personal narrative inquiry. Using research literature and studying four patient interactions through narrative
University of Lethbridge. Faculty of Education   +1 more
core  

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