Results 41 to 50 of about 2,248 (168)

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco, Troy D. Wood, Raymond Cha, Jill S. Hochreiter, Susan L. Rosenkranz, Mona Farhad, Kyle R. Whitson, Connor E. Gould, Lauren E. Hill, Linda L. Hale, Philip H. Lindhorst, Diala Ghazal, Charlene R. Taylor, Madiha Quraishi, Suzanne M. Siminski, Yoninah Cramer, Heather L. Sprenger, Gene D. Morse   +17 more
wiley   +1 more source

Unveiling the hidden clinical and economic impact of preanalytical errors

Türk Biyokimya Dergisi
The preanalytical phase is the basis upon which the accuracy and reliability of laboratory testing mostly depend. Despite many recent advancements in laboratory medicine, preanalytical errors remain the most common source of diagnostic inaccuracies ...
Lippi Giuseppe
doaj   +1 more source

Governance of Preanalytical Variability and Error Detection

Journal of Medical Biochemistry, 2008
Governance of Preanalytical Variability and Error ...
openaire   +2 more sources

Integrated ESR and PLT‐H Measurement Using the BC‐6800 Plus Hematology Analyzer: A Comprehensive Analytical Evaluation

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluated the analytical performance of the Mindray BC‐6800 Plus hematology analyzer, focusing on integrated erythrocyte sedimentation rate (ESR) and hybrid platelet counting (PLT‐H). Results demonstrated excellent background suppression, precision, linearity, and robustness across different modes and analyzers, confirming its reliability ...
Meilin Chen, Jinghai Yan, Manman Ye, Shihong Zhang, Xiaohe Zheng   +4 more
wiley   +1 more source

Variation in Laboratory Reports: Causes other than Laboratory Error

Journal of Nepal Medical Association, 2022
When a sample of an individual is measured at different times at the same or different clinical laboratory, the results are always different, even the state of health of an individual is the same. This disparity in the results from clinical laboratories
Santosh Pradhan, Keyoor Gautam, Vivek Pant   +2 more
doaj   +3 more sources

Novel opportunities for improving the quality of preanalytical phase: A glimpse to the future? [PDF]

Journal of Medical Biochemistry, 2017
The preanalytical phase is crucial for assuring the quality of in vitro diagnostics. The leading aspects which contribute to enhance the vulnerability of this part of the total testing process include the lack of standardization of different practices ...
Lippi Giuseppe, Cadamuro Janne
doaj  

Direct cost analysis for 32,783 samples with preanalytical phase errors

Northern Clinics of Istanbul, 2022
Errors in the laboratory process often occur in the preanalytical phase (PA). The study aims to calculate the direct cost elements of PA errors, including material, logistics, transfer, personnel workforce, and medical waste.Medical laboratory PA phase errors were retrospectively reviewed using the Laboratory Information Management System. We evaluated
openaire   +3 more sources

Prolonged Turnaround Time of the Hematology Laboratory and Related Factors in the South Gondar Zone, North West Ethiopia, Multi‐Centered Study

Journal of Clinical Laboratory Analysis, EarlyView.
Long turnaround times were prevalent in the hematology laboratories of South Gonder zone hospitals, predominantly as a result of staff incompetence. Clotted blood samples, low blood fill levels, and the day of the week were significant factors linked to delays, with samples collected on Friday having a higher likelihood of prolonged turnaround time ...
Birhanemaskal Malkamu, Getaneh Atikilt Yemata, Andargachew Almaw, Ayenew Berhan, Ayenew Assefa, Alemie Fentie, Birhanu Gete, Biruk Legese, Fanta Obsa, Gebyaw Arega, Habtamu Demelash, Tahir Eyayu, Teklehaimanot Kiros, Mahider Shimelis Feyisa, Mulat Erkihun, Mitikie Wondmagegn, Yenealem Solomon, Shewaneh Damtie, Tegenaw Tiruneh, Girum Tesfaye   +19 more
wiley   +1 more source

Improving wound swab collection in paediatric patients: a quality improvement project

BMJ Open Quality, 2023
Microbiology sample swabs may be unsuccessful or rejected for a variety of reasons. Typically, errors occur in the preanalytical phase of sample collection. Errors with collection, handling and transport can lead to the need to repeat specimen collection.
Ian Chin-Yee, Sean H Leonard, Johan Delport, Abby Crozier, Farah Abdulsatar   +4 more
doaj   +1 more source

Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p.A53T SNCA Mutation: Data from the Parkinson's Progression Markers Initiative Study

Movement Disorders, EarlyView.
Abstract Background Serum neurofilament light chain (NfL) levels, a marker of axonal damage, are generally elevated in neurodegenerative conditions, but results in idiopathic Parkinson's disease (iPD) have been inconsistent. The p.A53T SNCA mutation usually leads to a severe form of PD.
Nikolaos Papagiannakis, Christos Koros, Athina‐Maria Simitsi, Leonidas Stefanis, and The Parkinson's Progression Markers Initiative, Kenneth Marek, Tanya Simuni, Andrew Siderowf, Caroline Tanner, Thomas F Tropea, Tatiana Foroud, Lana Chahine, Brit Mollenhauer, Kalpana Merchant, Douglas Galasko, Christopher Coffey, Kathleen Poston, Roseanne Dobkin, Ethan Brown, Roy Alcalay, Dan Weintraub, Emily Flagg, Kimberly Fabrizio, Susan Bressman, Cornelis Blauwendraat, Paola Casalin, Sonya Dumanis, Raymond James, Karl Kieburtz, Sneha Mantri, Werner Poewe, Michael Schwarzschild, John Seibyl, David Standaert, Duygu Tosun‐Turgut, Sohini Chowdhury, Jamie Eberling, Mark Frasier, Leslie Kirsch, Katie Kopil, Maggie Kuhl, Alyssa O'Grady, Todd Sherer, Tawny Willson, Tanya Simuni, Bridget McMahon, Craig Stanley, Kim Fabrizio, Dixie Ecklund, Christine Kohnen, Tatiana Foroud, Laura Heathers, Christopher Hobbick, John Seibyl, Christopher Coffey, Chelsea Caspell‐Garcia, Michael Brumm, Arthur Toga, Karen Crawford, Tatiana Foroud, Jan Hamer, Brit Mollenhauer, Doug Galasko, Kalpana Merchant, Andrew Singleton, Tatiana Foroud, Dirk Keene, Caroline Tanner, Ethan Brown, Carlie Tanner, Ethan Brown, Lana Chahine, Roseann Dobkin, Monica Korell, Neha Prakash, Tanya Simuni, Nabila Dahodwala, Caroline Tanner, Lana Chahine, Brit Mollenhauer, Sebastian Schade, Douglas Galasko, Anat Mirelman, Roy Alcalay, Katherine Leaver, Marie Saint‐Hilaire, Ruth Schneider, Christopher Tarolli, Werner Poewe, Aleksandar Videnovic, David Standaert, Marissa Dean, Sonja Jonsdottir, Rejko Krueger, Claire Pauly, Stewart Factor, Penelope Hogarth, Robert Hauser, Amy Amara, Michelle Fullard, Cyrus Zabetian, Hubert Fernandez, Kathrin Brockmann, Isabel Wurster, Yen Tai, Paolo Barone, Marina Picillo, Stuart Isaacson, Alberto Espay, Eduardo Tolosa, Javier Ruiz Martinez, Leonidas Stefanis, Kelvin Chou, Lorraine Kalia, Connie Marras, David Grimes, Tiago Mestre, Rajesh Pahwa, Mark Lew, Holly Shill, Shyamal Mehta, Giulietta Riboldi, Nikolaus McFarland, Ron Postuma, Zoltan Mari, David Ledingham, Nicola Pavese, Michele Hu, Norbert Brueggemann, Christine Klein, Bastiaan Bloem, Cristina Simonet, Alastair Noyce, Anette Janzen, David Pedrosa, Wolfgang Oertel, Njideka Okubadejo, David Shprecher, Arjun Tarakad, Emile Moukheiber, Joy Antala, Carla Aranda, Karen Williams, Sophia Melton, Karina Benson, Ashwini Ramachandran, Danielle Potts, Grace LaMoure, Ritikha Vengadesh, Ryan Manzler, Jaime Heller, Primi Ranola, Farah Kausar, Sherri Mosovsky, Diana Willeke, Elizabeth Kalinkara Gomez, Janelle Rodriguez, Nobuko Kemmotsu, May Eshel, Deborah Raymond, Abigail Desrosiers, Raymond James, Lauren Jackson, Iris Egner, Wesley Schlett, Courtney Blair, Lauren Ruffrage, Berenice Sevilla, Barbara Sommerfeld, Dustin Le, Erica Botting, Gabriella Mazur, Daniele Derlein, Evan Doll, Ying Liu, Ciera Cobb, Olivia Masiewicz, Jennifer Mule, Michael Morsillo, Ella Hilt, Aldazier Jakiran, Dominga Valentino, Lisbeth Pennente, Bobbie Stubbeman, Alicia Garrido, Valeria Ravasi, Ioana Croitoru, Christos Koros, Nikolas Papagiannakis, Frank Ferrari, Mengyu Zheng, Shawna Reddie, Alicia Alejandra, Andrea Gray, Alejandra Valenzuela, Caitlin Goodman, Sara Dresler, Neil Santos, Fahrial Esha, Kyle Rizer, Nadine Zablith, Liliana Dumitrescu, Debra Galley, Victoria Kate Foster, Jamil Razzaque, Madita Grümmer, Yara Krasowski, Natalie Donkor, Elisabeth Sittig, Oluwadamilola Ojo, Kelly Clark, Rory Mahabir, Kori Ribb, Shamera Willoughby   +213 more
wiley   +1 more source