Results 131 to 140 of about 31,685 (237)

Understanding cancer from the perspective of cellular adaptation to stressors for survival

open access: yes
Quantitative Biology, Volume 14, Issue 3, September 2026.
Zhenyu Huang, Xuechen Mu, Ying Xu
wiley   +1 more source

Diagnostic accuracy of phosphatase and tensin homolog loss in differentiating between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia and non‐atypical endometrial hyperplasia: A systematic review and meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 630-642, August 2026.
Abstract Background Accurate distinction between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia (AH/EIN) and non‐atypical endometrial hyperplasia (EH) determines whether patients require hysterectomy or can be managed conservatively.
Kristina Shcherbatiuk   +6 more
wiley   +1 more source

Luteolin improves precancerous conditions of the gastric mucosa by binding STAT3 and inhibiting LCN2 expression. [PDF]

open access: yesInt J Biol Sci
Hao X   +17 more
europepmc   +1 more source

Photodynamic Therapy for Facial Rejuvenation Combined Amber LED and Infrared Laser Irradiation: A Pilot Study Comparing ALA and MAL

open access: yesJournal of Biophotonics, Volume 19, Issue 8, August 2026.
Topical ALA‐ and MAL‐based photodynamic protocols combined with amber light and infrared irradiation produced distinct PpIX fluorescence profiles in photoaged skin, revealing different photodynamic responses and supporting their potential use as complementary strategies for skin rejuvenation and improvement of photoaging‐related strategies.
Tassia Joi Martins   +4 more
wiley   +1 more source

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao   +4 more
wiley   +1 more source

Oral Microbial and Metabolic Alterations in Patients With Oral Lichen Planus Concomitant With Type 2 Diabetes Mellitus

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
We conducted a cross‐sectional study involving three groups: OLP‐DM, OLP, and healthy controls. Salivary 16S rRNA sequencing and untargeted metabolomics revealed distinct microbial and metabolic profiles among groups, which were associated with disease severity.
Xiaomeng Ren   +5 more
wiley   +1 more source

The impact of physiological oxidants on triggering amyloid formation of the cell cycle regulator protein p16INK4A

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract The tumor suppressor protein p16INK4a plays a key role in cell cycle control and is frequently inactivated in human cancers. We previously discovered that oxidation of its single cysteine residue induces a structural transition from the functional monomeric form into inactive amyloid fibrils.
Briana R. Smith   +6 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 4880-4897, August 2026.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

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