Results 151 to 160 of about 47,171 (271)
Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay +4 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
ABSTRACT Background The gingiva and floor of the mouth are distinct subsites, and oral squamous cell carcinoma (OSCC) originating in these locations warrants further indepth understanding. Methods This study enrolled patients with OSCC from 2000 to 2020, and analyzed the clinicopathological characteristics.
Hao Li +12 more
wiley +1 more source
The Value of DNA Quantitative Cytology Test for the Screening of Endometrial Cancer
Bao-hua Yang,1 Ming-xia Yu,1 Jun Xu,1 Yan Su,1 Zhi-hong Ai2 1Department of Obstetrics and Gynecology, Shanghai Minhang Central Hospital, Shanghai 201199, People’s Republic of China; 2Department of Obstetrics and Gynecology, Shanghai Jiao Tong ...
Yang B, Yu M, Xu J, Su Y, Ai Z
doaj
Juvenile polyposis in a SMAD4‐mutated child: A call for early surveillance
Abstract We report the case of a 10‐year‐old boy with hereditary hemorrhagic telangiectasia (HHT) and a family history of SMAD4‐related juvenile polyposis syndrome (JPS), presenting with hypoferritinaemia unresponsive to oral supplementation. Endoscopic evaluation revealed multiple gastrointestinal polyps, including duodenal, gastric, and colonic ...
Claudia Lorusso +10 more
wiley +1 more source
GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta‐Analysis
ABSTRACT Objective Gastroesophageal reflux disease (GERD) is highly prevalent, yet its association with upper aerodigestive tract (UADT) cancers beyond esophageal adenocarcinoma remains incompletely defined. This systematic review and meta‐analysis aimed to quantify the risk of specific UADT cancers in individuals with GERD.
Janice Huang +10 more
wiley +1 more source
Systemic Oxidative and Protein Profile Dysregulation in Tobacco-Associated Oral Malignancy and Precancerous Conditions. [PDF]
Padol MV +6 more
europepmc +1 more source
ABSTRACT Functional DNA methylation abnormalities are a hallmark of human cancers and may be a promising biomarker for their early diagnosis. Moreover, the largest methylation differences can improve the sensitivity of noninvasive diagnoses of solid tumors.
Junsheng Zhao +6 more
wiley +1 more source
Mitochondria-Associated Pathways in Cancer and Precancerous Conditions: Mechanistic Insights. [PDF]
Li L, Pan D, Ai R, Zhou Y.
europepmc +1 more source

