Results 61 to 70 of about 3,527 (306)

Stochastic Machine Scheduling with Precedence Constraints [PDF]

SIAM Journal on Computing, 2005
We consider parallel, identical machine scheduling problems where the jobs are subject to precedence constraints, release dates, and the processing times of jobs are governed by independent probability distributions. The objective is to minimize the expected value of the total weighted completion time `&; w_j C_j, where w_jgeq 0`.
Skutella Martin, Uetz Marc
openaire   +5 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Multi-Objective Optimization for a Partial Disassembly Line Balancing Problem Considering Profit and Carbon Emission

Mathematics
Disassembly lines are widely utilized to disassemble end-of-life products. Most of the research focuses on the complete disassembly of obsolete products. However, there is a lack of studies on profit and on carbon emission saved.
Wanlin Yang, Zixiang Li, Chenyu Zheng, Zikai Zhang, Liping Zhang, Qiuhua Tang   +5 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Assessing by Simulation the Effect of Process Variability in the SALB-1 Problem

AppliedMath, 2023
The simple assembly line balancing (SALB) problem is a significant challenge faced by industries across various sectors aiming to optimise production line efficiency and resource allocation.
Luis A. Moncayo-Martínez, Elias H. Arias-Nava   +1 more
doaj   +1 more source

INCREMENTAL FILTERING ALGORITHMS FOR PRECEDENCE AND DEPENDENCY CONSTRAINTS [PDF]

International Journal on Artificial Intelligence Tools, 2006
Precedence constraints specify that an activity must finish before another activity starts and hence such constraints play a crucial role in planning and scheduling problems. Many real-life problems also include dependency constraints expressing logical relations between the activities – for example, an activity requires presence of another activity ...
Roman Barták, Ondrej Cepek
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Developing assessment flow for damage estimation of mud housing typology through a case study against coastal floods

Scientific Reports, 2023
Rising instances of prolonged inundation due to climate-aggravated high tide flooding are economically burdensome for resource-crunched developing nations that bear enormous damage due to loss of built infrastructure (housing in this case). Regardless of
N. Aishwarya, K. Aniruddha, D. Sutapa, H. A. Bharath   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source