Results 61 to 70 of about 107,320 (311)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
US legal system in the context of English legal heritage and theory of the natural rights of John Locke [PDF]
Strani pravni život, 2018 The paper discusses several characteristics of the US legal system that rest upon English legal heritage, brought from England to North America by the first colonists.
Bekčić-Pješčić Gordana
doaj
Revista Eletrônica de Direito Processual, 2020 The present essay examines the nature of the creation activities contained in the decisions listed in article 927 of the Brazilian Civil Procedure Code of 2015 (BCPC/15) and its possible consequences for the Brazilian constitutional jurisdiction, as well
Romulo Ponticelli Giorgi Júnior
doaj +1 more source
Litigant Resources and the Evolution of Legal Precedent [PDF]
This paper develops an informational model of litigation in which court decisions are a function of legal representation. In this model, resource constraints determine how much parties expend on legal representation.
Richard Startz, Albert Yoon
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Revista Chilena de Derecho, 2010 Se discute el impacto de las decisiones del Tribunal Constitucional, en su rol de supremo intérprete de la Constitución, sobre los demás poderes del Estado, particularmente sobre el Gobierno y el Congreso, en especial cuando sus sentencias versan sobre ...
GONZALO CARREÑO PAVEZ +1 more
doaj
Precedent-free fault isolation in a diesel engine exhaust gas recirculation system
, 2012 In this paper, a recently introduced model-based method for precedent-free fault detection and isolation (FDI) is modified to deal with multiple input, multiple output (MIMO) systems and is applied to an automotive engine with exhaust gas recirculation ...
Cholette, Michael E. +1 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
, 2016 This Essay explores which legal precedent judges choose to support their decision. When describing the legal landscape in a written opinion, which precedent do judges gravitate toward?
Niblett, Anthony, Yoon, Albert H.
core +1 more source