Results 71 to 80 of about 107,320 (311)

Extending Trade Law Precedent

open access: yes, 2021
Precedent is celebrated as a fundamental feature of dense legal systems as it creates predictability, builds coherence, and enhances the authority of courts and tribunals.
Kucik, Jeffrey, Puig, Sergio
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Philosophy of Precedent: Conceptual Analysis and Rational Reconstruction

open access: yes, 2012
The paper purports to provide a few redefinitions of key terms in the theory of precedent ('precedent', 'ratio decidendi', 'obiter dictum') and a framework of abstract models about precedent de iure ...
CHIASSONI, PIERLUIGI
core  

Unprecedented Precedent: The Case Against Unreasoned “Shadow Docket” Precedent

open access: yes, 2023
Waldhauser, Cole. (2023). Unprecedented Precedent: The Case Against Unreasoned “Shadow Docket” Precedent.
Waldhauser, Cole
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

RACIAL SEGREGATION AS A MANIFESTATION OF IDEOLOGICAL EXTREMISM: THE EXAMPLE OF THE CASE “PLESSY V. FERGUSON” [PDF]

open access: yesLegal Bulletin
Relevance. The topic of racial segregation and the struggle for civil rights in the United States continues to be relevant. Precedential decisions of the US Supreme Court on issues of racial segregation still influence the development of American society
KHAPCHAEV S.T., KOKOREV V.G.
doaj   +1 more source

Overruling and the Instability of Law [PDF]

open access: yes
We investigate the evolution of common law under overruling, a system of precedent change in which appellate courts replace existing legal rules with new ones.
Andrei Shleifer, Nicola Gennaioli
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

THE OVERALL REPERCUSSIONS IN THE NEW CPC: THE CONSTRUCTION OF THE BINDING DECISION OF MERIT IN OVERALL REPERCUSSIONS BY STF

open access: yesRevista Eletrônica de Direito Processual, 2017
This article has the purpose to analyze the overall repercussions in the new code of civil procedure, its relationship with the mandatory precedent and the correlation with the new writings of arts.
Vinícius Silva Lemos
doaj   +1 more source

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