Results 151 to 160 of about 163,476 (344)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Learning While Setting Precedents

open access: yes
A decision maker makes a ruling on a random case in each period. She is uncertain about the correct ruling until conducting a costly investigation. A ruling establishes a precedent, which cannot be violated under binding precedent.
Chen, Ying, Eraslan, Hülya
core  

Introduction [Cohabitation : law, practice and precedents]

open access: yes, 2009
The numbers of unmarried cohabiting couples continues to increase meaning that the law and practice relating to this area continues to grow in significance for family and private client lawyers. This new edition of the popular "Cohabitation: Law Practice
Probert, Rebecca
core  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Precedent names in Chinese discourse

open access: yesRussian journal of linguistics: Vestnik RUDN, 2008
The paper deals with the names-precedents of the Chinese discourse. The names-precedents mean names which are connected with the widely known text or with situation-precedent and are known to every member of the Chinese lingvocultural community.
N N Voropaev
doaj  

Hinds' precedents of the House of Representatives of the United States : including references to provisions of the Constitution, the laws, and decisions of the United States Senate /

open access: yes, 1907
Continued by: Cannon's precedents of the House of Representatives of the United States ... volumes VI-XI, the last 3 v. of which are an index-digest to the complete work.A reprint from the original plates of the first 5 v.
Cannon, Clarence, 1879-1964. Cannon's precedents of the House of Representatives of the United States.   +1 more
core  

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

A Critical Analysis of Precedents on Child Evidence in Child Abuse Cases

open access: yesPakistan Journal of Islamic Research
The evidence is a tool to determine the innocence and guilt of any accused in a criminal trial. The trials of child sexual abuse cases are always a difficult job to do.
Nadia Zafar
doaj  

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

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