Results 41 to 50 of about 21,024 (265)

Topography-induced flows in a sidewall-modified, rapidly rotating and precessing cylinder

open access: yesEarth and Planetary Physics
The influence of topography on rotating fluids may exceed conventional expectations. Here, we numerically examine viscous incompressible flows induced by sidewall topography, confined within a modified cylinder that rotates rapidly about its central ...
XiuYu Chen   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Comparison of Libration- and Precession-Driven Flows: From Linear Responses to Broadband Dynamics

open access: yesFluids
Libration and precession are different body forces that are ubiquitous in many rapidly rotating systems, particularly in geophysical and astrophysical flows.
Ke Wu, Bruno D. Welfert, Juan M. Lopez
doaj   +1 more source

Precessing Jet in the High-Redshift Blazar J0017+8135

open access: yesGalaxies, 2016
The prominent flat-spectrum radio quasar J0017+8135 (S5 0014+81) at z = 3.366 is one of the most luminous active galactic nuclei (AGN) known. Its milliarcsecond-scale radio jet structure has been studied with very long baseline interferometry (VLBI ...
Kristóf Rozgonyi, Sándor Frey
doaj   +1 more source

A Precessing Jet in L1551 [PDF]

open access: yesSymposium - International Astronomical Union, 1987
An analysis of published observations of the L1551 optical jet leads to the conclusion that the driving region is very small, possibly little larger than the star itself. Further the data suggest that the jet is precessing.
openaire   +1 more source

Precession Motion in Levitated Optomechanics [PDF]

open access: yesPhysical Review Letters, 2018
We investigate experimentally the dynamics of a non-spherical levitated nanoparticle in vacuum. In addition to translation and rotation motion, we observe the light torque-induced precession and nutation of the trapped particle. We provide a theoretical model, which we numerically simulate and from which we derive approximate expressions for the ...
Ulbricht, Hendrik   +3 more
openaire   +6 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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