Results 181 to 190 of about 2,451 (297)

Estimation of Atmospheric Precipitable Water Using the Global Positioning System

, 2002
This research focuses on using the Global Positioning System (GPS) for atmospheric precipitable water (PW) estimation. Water vapor, measured in terms of PW, plays a crucial role in atmospheric processes and short-term weather forecasting.
Garay, David A.
core  

Candidate Sites for Millimeter and Submillimeter Ground-Based Telescopes: Atmospheric Rating for the Eurasian Submillimeter Telescopes Project. [PDF]

Sensors (Basel)
Shikhovtsev AY, Kovadlo PG, Baron P.
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Negative CO₂ emissions for long-term mitigation of extremes in land hydrological cycle. [PDF]

Nat Commun
Shin J, Kug JS, Park SW, Kam J, An SI, Park SE, Oh H, Yeh SW, Jeong S, Park CK, Kim JS.   +10 more
europepmc   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Possible influence of human activity on the daily maximum precipitation events over the Three-River Headwaters region of the Tibetan Plateau. [PDF]

Sci Rep
Lu X, Zhong D, Ren G, Zhang M, Li H, Tysa SK.   +5 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Human-induced climate change amplification on storm dynamics in Valencia's 2024 catastrophic flash flood. [PDF]

Nat Commun
Calvo-Sancho C, Díaz-Fernández J, González-Alemán JJ, Halifa-Marín A, Miglietta MM, Azorin-Molina C, Prein AF, Montoro-Mendoza A, Bolgiani P, Morata A, Martín ML.   +10 more
europepmc   +1 more source

Machine learning-based spatial data development for optimizing astronomical observatory sites in Indonesia. [PDF]

PLoS One, 2023
Sakti AD, Zakiar MR, Santoso C, Windasari NA, Jaelani AT, Damayanti S, Anggraini TS, Putri AD, Hudalah D, Deliar A.   +9 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source