Results 111 to 120 of about 1,623,514 (364)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Estimating the concentration of silver iodide needed to detect unambiguous signatures of glaciogenic cloud seeding [PDF]

open access: yesAtmospheric Chemistry and Physics
Detecting an unambiguous radar reflectivity signature is vital for investigating cloud-seeding impacts. The radar reflectivity change attributed to seeding depends on both the cloud conditions and the concentration of silver iodide (AgI) particles.
J. Yang   +15 more
doaj   +1 more source

A Review of Global Precipitation Data Sets: Data Sources, Estimation, and Intercomparisons [PDF]

open access: yes, 2018
In this paper, we present a comprehensive review of the data sources and estimation methods of 30 currently available global precipitation data sets, including gauge-based, satellite-related, and reanalysis data sets.
Ashouri, H   +5 more
core   +1 more source

Precipitation of Salts [PDF]

open access: yesThe Journal of Physical Chemistry, 1897
n ...
openaire   +2 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Microphysical Characteristics of Melting Layers in North China Revealed by Aircraft and Radar

open access: yesRemote Sensing
The microphysical processes within the melting layer (ML) of stratiform clouds have been understudied, particularly regarding their intricate properties and behaviors.
Xiangfeng Hu   +8 more
doaj   +1 more source

Can Mg isotopes be used to trace cyanobacteria-mediated magnesium carbonate precipitation in alkaline lakes? [PDF]

open access: yes, 2011
The fractionation of Mg isotopes was determined during the cyanobacterial mediated precipitation of hydrous magnesium carbonate precipitation in both natural environments and in the laboratory.
Balor, S.   +8 more
core   +3 more sources

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

An examination of the precipitation delivery mechanisms for Dolleman Island, eastern Antarctic Peninsula [PDF]

open access: yes, 2004
Copyright @ 2004 Wiley-BlackwellThe variability of size and source of significant precipitation events were studied at an Antarctic ice core drilling site: Dolleman Island (DI), located on the eastern coast of the Antarctic Peninsula.
ANDREW RUSSELL   +20 more
core   +1 more source

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