Results 91 to 100 of about 911,136 (315)

Influence of Black Carbon on Measurement Errors in Scattering-Based Visibility Meters

open access: yesAtmosphere
Visibility is a fundamental meteorological parameter critical for surface transportation, aviation, maritime navigation, and weather process investigation.
Zhihua Yang   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Precipitation downscaling in Canadian prairie provinces using the LARS-WG and GLM approaches

open access: yes, 2013
Two stochastic precipitation simulation models, namely the Long Ashton Research Station weather generator (LARS-WG) and a Generalized Linear Model-based weather generator (GLM-WG), are evaluated for downscaling daily precipitation at four selected ...
Chun, Kwok P.   +3 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Energetic particle precipitation into the middle atmosphere triggered by a coronal mass ejection [PDF]

open access: yes, 2007
Precipitation of relativistic electrons into the atmosphere has been suggested as the primary loss mechanism for radiation belt electrons during large geomagnetic storms.
Mccarthy, M.P.   +15 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Precipitation averaged across Europe, GPCC, 1914-1920 C.E.

open access: yes
DATA DESCRIPTION: Precipitation averaged across Europe, GPCC, 1914-1920 Citation: Alexander F. More, Christopher P. Loveluck, Heather Clifford, Michael J. Handley, Elena V. Korotkikh, Andrei V. Kurbatov, Michael McCormick and Paul A. Mayewski. (2020).
Global Precipitation Climatology Centre
core   +1 more source

Land use change suppresses precipitation

open access: yes, 2009
A feedback loop between regional scale deforestation and climate change was investigated in an experiment using novel, small size airborne platforms and instrument setups.
Junkermann, W   +11 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

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