Results 81 to 90 of about 1,064,125 (299)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

TEM Study of High-Temperature Precipitation of Delta Phase in Inconel 718 Alloy [PDF]

, 2011
Inconel 718 is widely used because of its ability to retain strength at up to 650◦C for long periods of time through coherent metastable γ” Ni3Nb precipitation associated with a smaller volume fraction of γ’ Ni3Al precipitates.
Dehmas, Moukrane, Aliou Niang, Niang, Aliou, Bernard Viguier, Viguier, Bernard, Moukrane Dehmas, Jacques Lacaze, Lacaze, Jacques   +7 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

THE SPECIFICITY OF SEROLOGICAL PRECIPITATION [PDF]

Journal of Experimental Medicine, 1946
Precipitative mixing experiments have been conducted with the aid of a turbidimeter and a darkfield microscope. The results of these experiments, correlated with observations of macroscopic features, indicate that serological precipitation is largely governed by a highly specific mechanism except in the terminal period, when the operation of non ...
openaire   +4 more sources

Exploring the mechanisms of dust emission and transport based on observations and GEOS-Chem simulations [PDF]

Atmospheric Chemistry and Physics
Dust aerosols play a significant role in climate and air quality, yet understanding of their emission and long-range transport mechanisms remains incomplete. By looking into a severe dust event occurred in northern China on April 2025, and conducting the
P. Zou, X. Ma, R. Tian, J. Zhao, T. Yang, Y. Ku   +5 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Precipitation downscaling in Canadian prairie provinces using the LARS-WG and GLM approaches

, 2013
Two stochastic precipitation simulation models, namely the Long Ashton Research Station weather generator (LARS-WG) and a Generalized Linear Model-based weather generator (GLM-WG), are evaluated for downscaling daily precipitation at four selected ...
Chun, Kwok P., Wheater, Howard S., Nazemi, A., Khaliq, M. N.   +3 more
core   +1 more source

Microphysical Characteristics of Melting Layers in North China Revealed by Aircraft and Radar

Remote Sensing
The microphysical processes within the melting layer (ML) of stratiform clouds have been understudied, particularly regarding their intricate properties and behaviors.
Xiangfeng Hu, Shaoyu Hou, Jiefang Yang, Shuwen Zhao, Xiaorui Zhang, Yue Tao, Hongyu Li, Xiaotuo Zhang, Hao Huang   +8 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source