Results 61 to 70 of about 911,136 (315)
Analysis of a Haze Event over Nanjing, China Based on Multi-Source Data
We analyzed a June 2018 Nanjing, China haze event using ground-based and spaceborne sensors, combined with sounding and HYSPLIT backward trajectory data, with the ground-based and spaceborne sensor data exhibiting good consistency.
Yiyang Zhang, Jing Wang, Lingbing Bu
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A uniformity index for the axis ratios (Uar) derived from dual polarization weather radar data is proposed for raindrop area identification and analysis. The derivation of this new parameter is based on radar scattering simulations and assumptions.
Yue Sun +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A Composite Approach for Evaluating Operational Cloud Seeding Effect in Stratus Clouds
Robust water management is in intense demand in many water scarcity areas, such as arid and semi-arid regions in the world. As part of the regional water management strategy, rain enhancement is vital to replenish groundwater reservoirs, and the key ...
Fei Wang +7 more
doaj +1 more source
Changes in the Distribution Pattern of PM2.5 Pollution over Central China
The extent of PM2.5 pollution has reduced in traditional polluted regions such as the North China Plain (NCP), Yangtze River Delta (YRD), Sichuan Basin (SB), and Pearl River Delta (PRD) over China in recent years.
Lijuan Shen +6 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Derivation of the reduced reaction mechanisms of ozone depletion events in the Arctic spring by using concentration sensitivity analysis and principal component analysis [PDF]
The ozone depletion events (ODEs) in the springtime Arctic have been investigated since the 1980s. It is found that the depletion of ozone is highly associated with an auto-catalytic reaction cycle, which involves mostly the bromine-containing ...
L. Cao +4 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

