Results 201 to 210 of about 1,294,782 (279)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Carbonate burial regimes, the Meso-Cenozoic climate, and nannoplankton expansion. [PDF]

open access: yesProc Natl Acad Sci U S A
Salles T   +7 more
europepmc   +1 more source

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

open access: yesAdvanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang   +7 more
wiley   +1 more source

Chemical controls on iron distributions across the subsurface South Pacific Ocean. [PDF]

open access: yesNat Commun
Gledhill M   +8 more
europepmc   +1 more source

Soil Inorganic Electron Acceptors and Carbon Substrates Hierarchically Govern Wetland Methanogenesis Temperature Response

open access: yesAdvanced Science, EarlyView.
ABSTRACT Wetlands constitute Earth's largest natural methane (CH4) source, yet projections of their climate feedback remain uncertain due to poorly constrained temperature sensitivity (Q10‐CH4) of microbial methanogenesis. While water table dynamics have been demonstrated to regulate wetland methanogenesis by altering key soil conditions such as ...
Shuying Qiu   +6 more
wiley   +1 more source

Aragonite lithium/magnesium as an indicator of calcification media saturation state in marine calcifiers. [PDF]

open access: yesCommun Earth Environ
Castillo Alvarez C   +6 more
europepmc   +1 more source

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