Results 131 to 140 of about 2,642,880 (286)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
OPERATIONAL ASPECTS OF ORBIT DETERMINATION WITH GPS FOR SMALL SATELLITES WITH A SAR PAYLOAD. [PDF]
, 2005 Scientific small satellite missions for remote sensing with Synthetic Aperture Radar (SAR) payloads or high accuracy optical sensors, pose very strict requirements on the accuracy of the reconstructed satellite positions, velocities and accelerations ...
Zehetbauer, Tino +2 more
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Improving the GRACE Kinematic Precise Orbit Determination Through Modified Clock Estimating. [PDF]
Sensors (Basel), 2019 Zhou X, Jiang W, Chen H, Li Z, Liu X.
europepmc +1 more source
Precise orbit determination for GPS satellites [PDF]
, 1990 The NAVSTAR Global Positioning System (GPS) has been under development by the US Department of Defense since 1973. Although GPS was developed for precise instantaneous position and velocity determination, it can be used for high precision relative positioning, with numerous applications for both surveyors and geodesists.
openaire +1 more source
Orbit Determination System for Low Earth Orbit Satellites [PDF]
, 2007 The IAI/MBT Precise Orbit Determination system for Low Earth Orbit satellites is presented. The system is based on GPS pesudorange and carrier phase measurements and implements the Reduced Dynamics method.
Elisha, Yossi +2 more
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
New-Generation BeiDou (BDS-3) Experimental Satellite Precise Orbit Determination with an Improved Cycle-Slip Detection and Repair Algorithm. [PDF]
Sensors (Basel), 2018 Hu C +3 more
europepmc +1 more source