GOCE precise orbit determination for the entire Mission – challenges in the final mission phase [PDF]
The Gravity field and steady-state Ocean Circulation Explorer (GOCE), ESA’s first Earth Explorer core mission, was launched on March 17, 2009 into a sunsynchronous dusk-dawn orbit and eventually re-entered into the Earth’s atmosphere on November 11, 2013.
Bock, Heike +2 more
core
Research on the impact factors of GRACE precise orbit determination by dynamic method [PDF]
With the successful use of GPS-only-based POD (precise orbit determination), more and more satellites carry onboard GPS receivers to support their orbit accuracy requirements.
Kai Li, Nan-nan Guo, Xu-hua Zhou, Bin Wu
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Precise orbit determination for Alba CubeSat using Satellite Laser Ranging [PDF]
openL'argomento principale trattato nel seguente elaborato è la Determinazione orbitale di un satellite artificiale. Il satellite in questione è il prodotto del lavoro del team studentesco Alba Cubesat Unipd, partecipante al progetto ESA "Fly your ...
ZULLI, ELEONORA
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Kinematic and reduced-dynamic precise orbit determination of low earth orbiters [PDF]
Various methods for kinematic and reduced-dynamic precise orbit determination (POD) of Low Earth Orbiters (LEO) were developed based on zero- and double-differencing of GPS carrier-phase measurements with and without ambiguity resolution.
D. Švehla, M. Rothacher
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Orbit Determination via a Deeply- Coupled UKF/GNSS Filter [PDF]
This paper is dedicated to determining the orbit of a satellite by using Unscented Kalman Filter (UKF), in which, a GNSS is used as the observation sensor.
MohammadAli Amiri Atashgah +2 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source

