Results 101 to 110 of about 2,510,789 (285)

Onboard orbit determination using GPS measurements for low Earth orbit satellites [PDF]

, 2005
Recent advances in spaceborne GPS technology have shown significant advantages in many aspects over conventional technologies. For instance, spaceborne GPS can realize autonomous orbit determination with significant savings in spacecraft life cycle, in ...
Zhou, Ning
core  

Precise relative orbit determination of twin GRACE satellites

Geo-spatial Information Science, 2010
When formation flying spacecrafts are used as platform to gain earth oriented observation, precise baselines between these spacecrafts are always essential. Gravity recovery and climate experiment (GRACE) mission is aimed at mapping the global gravity field and its variation.
Qile Zhao, Zhigang Hu, Jing Guo 0005, Min Li, Maorong Ge   +4 more
openaire   +2 more sources

Effect of lunar gravity models on Chang'E-2 orbit determination using VLBI tracking data

Geodesy and Geodynamics, 2016
The precise orbit determination of Chang'E-2 is the most important issue for successful mission and scientific applications, while the lunar gravity field model with big uncertainties has large effect on Chang'E-2 orbit determination.
Erhu Wei, Xuechuan Li, Shuanggen Jin, Jingnan Liu   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Precise Orbit Determination of Low Earth Satellites at AIUB using GPS and SLR [PDF]

, 2013
An ever increasing number of low Earth orbiting (LEO) satellites is, or will be, equipped with retro-reflectors for Satellite Laser Ranging (SLR) and on-board receivers to collect observations from Global Navigation Satellite Systems (GNSS) such as ...
Thaller, Daniela, Baumann, Christian, Dach, Rolf, Bock, Heike, Meyer, Ulrich, Jäggi, Adrian, Sosnica, Krzysztof Jakub   +6 more
core   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Accuracy Assessment of SGP4 Orbit Information Conversion into Osculating Elements [PDF]

, 2013
The SGP4 model is one of the analytical orbit models applied for the orbit prediction using TLE orbit information. For the orbit accuracy improvement, a model conversion was performed to apply a more precise model. Assuming that a TLE data set is the
Aida, Saika, Kirschner, Michael
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Estimating maneuvers for precise relative orbit determination using GPS

, 2016
Precise relative orbit determination is an essential element for the generation of science products from distributed instrumentation of formation flying satellites in low Earth orbit. According to the mission profile, the required formation is typically
Urs Hugentobler, Jean-Sébastien Ardaens, Gerardo Allende-Alba, Allende Alba, Gerardo, Hugentobler, Urs, Oliver Montenbruck, Ardaens, Jean-Sébastien, Montenbruck, Oliver, Wermuth, Martin, Martin Wermuth   +9 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source