Results 81 to 90 of about 99,959 (290)

STE-QUEST Mission and System Design - Overview after completion of Phase-A

, 2014
STE-QUEST is a fundamental science mission which is considered for launch within the Cosmic Vision programme of the European Space Agency (ESA). Its main scientific objectives relate to probing various aspects of Einstein's theory of general relativity ...
Beck, Jan, Hechenblaikner, Gerald, Hess, Marc-Peter, Vitelli, Marianna   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Approaches to CHAMP precise orbit determination

, 2003
With a tailored gravity field model, the dynamic restitution of the CHAMP orbit can be carried out quite accurately. The solution can be based on the onboard accelerometer data or on dynamical models with additional parameters. Beside the dynamic mode, also a geometric/kinematic satellite position determination is implemented in the GFZ POD software ...
Neumayer, K., König, R., Zhu, S.
openaire   +4 more sources

Office of Spaceflight Standard Spaceborne Global Positioning System (GPS) user equipment project [PDF]

The Global Positioning System (GPS) provides the following: (1) position and velocity determination to support vehicle GN&C, precise orbit determination, and payload pointing; (2) time reference to support onboard timing systems and data time tagging; (3)
Saunders, Penny E.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

TRIFLE DIFFERENCE APPROACH TO LOW EARTH ORBITER PRECISION ORBIT DETERMINATION

Journal of Astronomy and Space Sciences, 2003
A precise kinematic orbit determination (P-KOD) procedure for Low Earth Orbiter(LEO) using the GPS ion-free triple differenced carrier phases is presented. Because the triple differenced observables provide only relative information, the first epoch`s positions of the orbit should be held fixed. Then, both forward and backward filtering was executed to
Jay Hyoun Kwon, Dorota A. Grejner-Brezinska, Jae Hong Yom, Dong Cheon Lee   +3 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Precise Orbit Determination for ALOS [PDF]

The Advanced Land Observing Satellite (ALOS) has been developed to contribute to the fields of mapping, precise regional land coverage observation, disaster monitoring, and resource surveying.
Katagiri, Seiji, Kudo, Nobuo, Nakamura, Ryo, Nakamura, Shinichi   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Precise Orbit Determination of GPS Satellites Using Phase Observables [PDF]

Journal of Astronomy and Space Sciences, 1997
The accuracy of user position by GPS is heavily dependent upon the accuracy of satellite position which is usually transmitted to GPS users in radio signals.
Myung-Kook Jee, Kyu-Hong Choi, Pil-Ho Park   +2 more
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