Results 171 to 180 of about 101,629 (318)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Precise Point Positioning Algorithm for Pseudolite Combined with GNSS in a Constrained Observation Environment. [PDF]
Sensors (Basel), 2020 Sheng C, Gan X, Yu B, Zhang J.
europepmc +1 more source
Performance of Real-Time Precise Point Positioning
, 2013 The IGS Real-time Pilot Project (IGS-RTPP) provides real-time precise orbits and clocks, which support real-time positioning for single stations over large areas using the Precise Point Positioning (PPP) technique.
Hu, Congwei +5 more
core
Correction Model of BDS-3 Satellite Pseudorange Multipath Delays and Its Impact on Single-Frequency Precise Point Positioning [PDF]
, 2021 Zhongchen Guo +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Post-Processing Precise Point Positioning Solutions with Parameter Optimization
, 2022 Maria A Gonzalez Castaneda
openalex +2 more sources
Precise point positioning with GPS and Galileo broadcast ephemerides [PDF]
, 2021 Luca Carlin +2 more
openalex +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source