Results 91 to 100 of about 1,892,828 (243)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
INFLUENCIA DE LA OPOSICIÓN EN LA PRECISIÓN DEL LANZAMIENTO EN JUGADORES SENIOR Y SUB-18 DE BALONMANO
E-balonmano.com: Revista de Ciencias del Deporte, 2011 Resumen La precisión así como la velocidad del balón determinan el éxito del lanzamiento en balonmano. Así, varios estudios han analizado la relación entre ambos factores, aunque ninguno incluyó la oposición del portero, desconociéndose su influencia ...
Jesús Rivilla-Garcia +2 more
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Relaciones Internacionales, 2012 El artículo presente realiza un recorrido histórico por las tensiones que se cernieron sobre el proceso de legalización internacional a propósito de las inversiones más allá de las fronteras nacionales.
José Marcelino FERNÁNDEZ ALONSO
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Problems of Accuracy in Legal Discourse (A Language Advice Service Approach) [PDF]
, 2015 In this article we are going to focus on what probably best defines legal writing: textual accuracy. Specifically, we address two, to an extent, opposing questions.
González Salgado, José Antonio
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Ganadería de precisión en vacuno lechero [PDF]
, 2015 La estructura de las granjas de vacuno de leche ha cambiado sustancialmente en los últimos 20 años, lo que ha conducido a un menor número de explotaciones, de mayor tamaño, más intensivas y con un mayor rendimiento por ...
Callejo Ramos, Antonio
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Un estudio sobre el monitor y la competencia comunicativa [PDF]
, 2017 El presente estudio examina la aplicación de la gramática en el proceso de autocorrección por escrito y su relación con la comunicación oral definida como fluidez y precisión oral.
Obilinovic, Katica
core +1 more source