Results 101 to 110 of about 1,969,076 (244)
Se reporta el uso de segmentos como dominio de integración para los métodos libres de mallas de tipo Petrov-Galerkin Local (MLPG). El procedimiento acarrea ventajas en el tratamiento de dominios con forma geométrica irregular, circunda el problema de la ...
Perez Sanchez, Ismay +2 more
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Radioterapia de alta precisión en el tratamiento del cáncer: Hadronterapia [PDF]
Excmo. Sr. Presidente, Excmos. e Ilmos. Sres. Académicos, colegas médicos, físicos y demás personas que han tenido a bien asistir a esta sesión científica que versará sobre la hadronterapia del cáncer.
Petschen Verdaguer, Ignacio
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Resolución de ambigüedades GPS: técnicas empleadas y estudios [PDF]
El fin de este artículo es una profundización en lo que se denomina en argot GPS, Resolución de la Ambigüedad. Ésta, es clave en mediciones GPS cuando se trabaja con técnicas estáticas de corta base o cinemáticas principalmente en tiempo real.
Martínez García, Juan José +1 more
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UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Background and Objectives: Malaria is a disease that can result in a variety of complications. Diagnosis is carried out by an optical microscope and depends on operator experience.
Eduardo Rojas +10 more
doaj +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Effects of species’ traits and data characteristics on distribution models of threatened invertebrates [PDF]
Efectos de las características ecológicas y de los datos sobre los modelos de distribución de invertebrados protegidos La escasez de información sobre la distribución de las especies amenazadas impide el desarrollo de estrategias para su conservación ...
Chefaoui, R. M., Hortal, J., Lobo, J. M.
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