Results 101 to 110 of about 1,969,076 (244)

The segments method [PDF]

open access: yes, 2008
Se reporta el uso de segmentos como dominio de integración para los métodos libres de mallas de tipo Petrov-Galerkin Local (MLPG). El procedimiento acarrea ventajas en el tratamiento de dominios con forma geométrica irregular, circunda el problema de la ...
Perez Sanchez, Ismay   +2 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Radioterapia de alta precisión en el tratamiento del cáncer: Hadronterapia [PDF]

open access: yes, 2007
Excmo. Sr. Presidente, Excmos. e Ilmos. Sres. Académicos, colegas médicos, físicos y demás personas que han tenido a bien asistir a esta sesión científica que versará sobre la hadronterapia del cáncer.
Petschen Verdaguer, Ignacio
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Resolución de ambigüedades GPS: técnicas empleadas y estudios [PDF]

open access: yes, 1998
El fin de este artículo es una profundización en lo que se denomina en argot GPS, Resolución de la Ambigüedad. Ésta, es clave en mediciones GPS cuando se trabaja con técnicas estáticas de corta base o cinemáticas principalmente en tiempo real.
Martínez García, Juan José   +1 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Computer Viewing Model for Classification of Erythrocytes Infected with Plasmodium spp. Applied to Malaria Diagnosis Using Optical Microscope

open access: yesMedicina
Background and Objectives: Malaria is a disease that can result in a variety of complications. Diagnosis is carried out by an optical microscope and depends on operator experience.
Eduardo Rojas   +10 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Effects of species’ traits and data characteristics on distribution models of threatened invertebrates [PDF]

open access: yes, 2011
Efectos de las características ecológicas y de los datos sobre los modelos de distribución de invertebrados protegidos La escasez de información sobre la distribución de las especies amenazadas impide el desarrollo de estrategias para su conservación ...
Chefaoui, R. M., Hortal, J., Lobo, J. M.
core  

Home - About - Disclaimer - Privacy