Results 101 to 110 of about 1,892,828 (243)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The segments method [PDF]

, 2008
Se reporta el uso de segmentos como dominio de integración para los métodos libres de mallas de tipo Petrov-Galerkin Local (MLPG). El procedimiento acarrea ventajas en el tratamiento de dominios con forma geométrica irregular, circunda el problema de la ...
Perez Sanchez, Ismay, Recarey Morfa, Carlos A., Viamontes Esquivel, Alcides   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Computer Viewing Model for Classification of Erythrocytes Infected with Plasmodium spp. Applied to Malaria Diagnosis Using Optical Microscope

Medicina
Background and Objectives: Malaria is a disease that can result in a variety of complications. Diagnosis is carried out by an optical microscope and depends on operator experience.
Eduardo Rojas, Irene Cartas-Espinel, Priscila Álvarez, Matías Moris, Manuel Salazar, Rodrigo Boguen, Pablo Letelier, Lucia San Martín, Valeria San Martín, Camilo Morales, Neftalí Guzmán   +10 more
doaj   +1 more source

Agricultura de precisión en EEUU y Argentina: dos ejemplos a seguir [PDF]

, 2002
Antes de entrar en detalle en estos dos ejemplos de agricultura de precisión, es importante dejar algunos conceptos claros o por lo j menos repasar ideas.
Valero Ubierna, Constantino
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Resolución de ambigüedades GPS: técnicas empleadas y estudios [PDF]

, 1998
El fin de este artículo es una profundización en lo que se denomina en argot GPS, Resolución de la Ambigüedad. Ésta, es clave en mediciones GPS cuando se trabaja con técnicas estáticas de corta base o cinemáticas principalmente en tiempo real.
Martínez García, Juan José, Torrecillas Lozano, Cristina   +1 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Antropología implacable

Revista Argentina de Antropología Biológica
La antropología, durante su institucionalización en el siglo XIX, adoptó y desarrolló un variado corpus instrumental a fin de reemplazar las descripciones de las variantes físicas humanas por números.
Marina L. Sardi, Mara Dettler, Lucía V. Arcidiácono   +2 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source