Results 81 to 90 of about 179,228 (306)

Persuasion with Precision: Using Natural Language Processing to Improve Instrument Fidelity for Risk Communication Experimental Treatments [PDF]

, 2022
Ann Marie Reinhold, Eric D. Raile, Clemente Izurieta, Jamie McEvoy, Henry King, Geoffrey C. Poole, Richard C. Ready, Nicolas T. Bergmann, Elizabeth A. Shanahan   +8 more
openalex   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Instruments of Precision at the Paris Exhibition [PDF]

, 1900

openalex   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Optimizing MEMS inertial switches for efficient event-based environmental interaction: motivation, approaches, and purposes

Microsystems & Nanoengineering
The rapid growth of the Internet of Things (IoT) and embodied intelligence has increased the demand for sensor nodes that conserve energy and reduce data transmission, especially in resource-limited applications that rely heavily on sensors.
Lyuyan Wang, Jiahao Zhao, Zheng You
doaj   +1 more source

Denoising Algorithm for High-Resolution and Large-Range Phase-Sensitive SPR Imaging Based on PFA

Sensors
Phase-sensitive surface plasmon resonance (SPR) detection is widely employed in molecular dynamics studies and SPR imaging owing to its real-time capability, high sensitivity, and compatibility with imaging systems. A key research objective is to achieve
Zihang Pu, Xuelin Wang, Wanwan Chen, Zhexian Liu, Peng Wang   +4 more
doaj   +1 more source

Distributed Strain and Temperature Discrimination Using Two Types of Fiber in OFDR

IEEE Photonics Journal, 2016
We present a simple and effective method to achieve a distributed strain and temperature discrimination using two types of fiber by a Rayleigh backscattering spectra (RBS) shifts in optical frequency domain reflectometry.
Zhenyang Ding, Di Yang, Yang Du, Kun Liu, Yonghan Zhou, Rao Zhang, Zhexi Xu, Junfeng Jiang, Tiegen Liu   +8 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Intermittent Visual Servoing: Efficiently Learning Policies Robust to Instrument Changes for High-precision Surgical Manipulation [PDF]

, 2020
Samuel Paradis, Minho Hwang, Brijen Thananjeyan, Jeffrey Ichnowski, Daniel Seita, Danyal Fer, Thomas Low, Joseph E. Gonzalez, Ken Goldberg   +8 more
openalex   +1 more source