Results 181 to 190 of about 1,176,394 (331)

Precision Medicine in Asthma: The Role of Biomarkers. [PDF]

Immunotargets Ther
Quek E, Horn N, Siddiqui S.
europepmc   +1 more source

What US Healthcare Providers Value in Genomic Precision Medicine: A Discrete Choice Experiment [PDF]

, 2018
DS Dhanda, Dean A. Regier, DL Veenstra, Anirban Basu, Jonathan Saha, Nathaniel Hendrix, JJ Carlson   +6 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Towards precision medicine

Acta Medica Lituanica, 2017
Sonata Jarmalaitė
doaj  

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Editorial: Radiomics Advances Precision Medicine

Frontiers in Oncology, 2022
Bo Gao, Di Dong, Huimao Zhang, Zaiyi Liu, Seyedmehdi Payabvash, Bihong T. Chen   +5 more
doaj   +1 more source

Multi-Omics Integration for Advancing Glioma Precision Medicine. [PDF]

Ann Clin Transl Neurol
Guarnaccia M, La Cognata V, Gentile G, Morello G, Cavallaro S.   +4 more
europepmc   +1 more source

Radiomics Approach for Cutaneous Melanoma Treatment Response Assessment in The Era of Precision Medicine [PDF]

, 2019
Antonino Guerrisi
openalex   +1 more source

A Bayesian precision medicine framework for calibrating individualized therapeutic indices in cancer

, 2022
Abhisek Saha, Min Jin Ha, Satwik Acharyya, Veerabhadran Baladandayuthapani   +3 more
openalex   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source