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Preparing for Precision Medicine
New England Journal of Medicine, 2012Precision medicine uses clinicopathological indexes and molecular profiling to create diagnostic, prognostic, and therapeutic strategies tailored to the patient. Its success depends on establishing frameworks for regulating, compiling, and interpreting key information.
Reza, Mirnezami +2 more
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Precision Medicine in Diabetes
2022Tailoring treatment or management to groups of individuals based on specific clinical, molecular, and genomic features is the concept of precision medicine. Diabetes is highly heterogenous with respect to clinical manifestations, disease progression, development of complications, and drug response.
Dawed, Adem Y. +2 more
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The Paradox of Precision Medicine
Scientific American, 2016The article focuses on the benefits and drawbacks of precision medicine. It comments on the cystic fibrosis drug ivacaftor which can treat around five percent of cystic fibrosis patients and was fast-tracked by the U.S. Food and Drug Administration in 2010, and mentions the drug costs 300,000 dollars a year per patient and could be treated equally ...
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Nature Reviews Genetics, 2016
There is great potential for genome sequencing to enhance patient care through improved diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, genomics strategies that have been developed for genetic discovery - including DNA-sequencing technologies and analysis algorithms - need to be adapted to fit clinical needs ...
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There is great potential for genome sequencing to enhance patient care through improved diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, genomics strategies that have been developed for genetic discovery - including DNA-sequencing technologies and analysis algorithms - need to be adapted to fit clinical needs ...
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Precision medicine in epilepsy
2022Epilepsy is a common neurological disorder affecting over 50 million people worldwide. Although more than 20 new anti-seizure medications have been developed in the past three decades, about one-third of patients still experience recurrent seizures. The heterogeneity of epilepsy types and the highly variable inter-individual response to the therapies ...
Ryan James, McGinn +3 more
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Personalizing precision medicine
Journal of the American Society of Hypertension, 2015Personalized medicine used to mean the individual attention each patient received from a caring physician, who took the time to explain the health problem, potential remedies, and attendant risks, and then administered the best possible treatment. We learned personalized medicine by observing master teachers and by practicing what they taught. The term
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Clinical management of metastatic colorectal cancer in the era of precision medicine
Ca-A Cancer Journal for Clinicians, 2022Fortunato Ciardiello +2 more
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Radiotheranostics in oncology: Making precision medicine possible
Ca-A Cancer Journal for Clinicians, 2023Eric O Aboagye +2 more
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