Results 251 to 260 of about 1,176,394 (331)

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Organoid Technology in Precision Medicine for Head and Neck Cancer. [PDF]

Oncol Res
Han B, Liu S, Das R, Liu S, Zhang Y.
europepmc   +1 more source

An ex vivo native environment precision medicine test shows high clinical correlation with responses to first line acute myeloid leukemia treatment

, 2016
Pau Montesinos, J. Ballesteros, David Martínez Cuadrón, Joaquín Martínez‐López, Josefina Serrano, Jaime Pérez de Oteyza, Paula Fernández, García Macías, María‐Belén Vídriales, Pilar Herrera, Mar Tormo, Juan Bergua, Rosella Garcia, Susana Vives, M N Fernández, Esperanza Lavilla, S Jiménez, JA Perez Simon, Adriana Simiele, Adam C. Gonzalez, Bernardo González, Carmen Burgaleta, J. Abraham Lopez, Concepción Bethancourt, G. Bautista, Aránzazu Alonso, Mercedes Colorado, J Sierra, Begoña Navas, JA Hernandez Rivas, JA Vera, Lauro Fabian Amador, Raúl Córdoba, A. de la Fuente, Fernanda Moraes Ramos, C.J. Cerveró, C Rayón, Olga Salamero, Elizabeth Marti, A Loez, Teresa Olavé, Marta Gaspar, Julián Gorrochategui, JL Rojas, Clara M. Gómez, P Hernández, Alicia Robles, Ignacio Ortega, Jesús Villoria, Federico Moscardó, Iñaki F. Trocóniz, Miguel Á. Sanz   +51 more
openalex   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Editorial: Hypertrophic Cardiomyopathy and Precision Medicine in Cardiovascular Disease. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

Serum cytokine levels towards precision medicine in Still’s disease: a subanalysis of a randomized controlled trial of tocilizumab

Koji Suzuki, Hideto Kameda, Kei Ikeda, Tomonori Ishii, Kosaku Murakami, Hyota Takamatsu, Yoshiya Tanaka, T. Abe, Tsutomu Takeuchi, Yuko Kaneko   +9 more
openalex   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Hydroxychloroquine's diverse targets: a new frontier in precision medicine. [PDF]

Front Immunol
Du B, Li L, Li J, Liu Y, Wang P.
europepmc   +1 more source

P-712 Precision medicine in IVF – positive impact on live birth rate [PDF]

Yvonne Lundberg Giwercman, Ida Hjelmér, Mathias Nilsson, Emir Hénic, Hannah Nenonen, A. Giwercman, Mariusz Kitliński   +6 more
openalex   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source