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Annals of Internal Medicine, 2016
Precision medicine aims to fix what is wrong with today’s healthcare: a lack of targeted interventions tailored to the person. It encompasses many aspects of health; chief among these is one’s genetic profile. Researchers are making progress as gene-sequencing technologies get better and cheaper.
M, Pacanowski, S M, Huang
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Precision medicine aims to fix what is wrong with today’s healthcare: a lack of targeted interventions tailored to the person. It encompasses many aspects of health; chief among these is one’s genetic profile. Researchers are making progress as gene-sequencing technologies get better and cheaper.
M, Pacanowski, S M, Huang
+9 more sources
Preparing for Precision Medicine
New England Journal of Medicine, 2012Precision medicine uses clinicopathological indexes and molecular profiling to create diagnostic, prognostic, and therapeutic strategies tailored to the patient. Its success depends on establishing frameworks for regulating, compiling, and interpreting key information.
Reza, Mirnezami +2 more
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Precision medicine in epilepsy
2022Epilepsy is a common neurological disorder affecting over 50 million people worldwide. Although more than 20 new anti-seizure medications have been developed in the past three decades, about one-third of patients still experience recurrent seizures. The heterogeneity of epilepsy types and the highly variable inter-individual response to the therapies ...
Ryan James, McGinn +3 more
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Precision medicine in cardiology
Nature Reviews Cardiology, 2016The cardiovascular research and clinical communities are ideally positioned to address the epidemic of noncommunicable causes of death, as well as advance our understanding of human health and disease, through the development and implementation of precision medicine.
Elliott M, Antman, Joseph, Loscalzo
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The Paradox of Precision Medicine
Scientific American, 2016The article focuses on the benefits and drawbacks of precision medicine. It comments on the cystic fibrosis drug ivacaftor which can treat around five percent of cystic fibrosis patients and was fast-tracked by the U.S. Food and Drug Administration in 2010, and mentions the drug costs 300,000 dollars a year per patient and could be treated equally ...
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Nature Reviews Genetics, 2016
There is great potential for genome sequencing to enhance patient care through improved diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, genomics strategies that have been developed for genetic discovery - including DNA-sequencing technologies and analysis algorithms - need to be adapted to fit clinical needs ...
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There is great potential for genome sequencing to enhance patient care through improved diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, genomics strategies that have been developed for genetic discovery - including DNA-sequencing technologies and analysis algorithms - need to be adapted to fit clinical needs ...
openaire +2 more sources
Precision Medicine for Insomnia
Sleep Medicine Clinics, 2019Insomnia affects up to 15% of the US population. There are effective pharmacologic and behavioral treatments for insomnia; however, there is often no one-size-fits-all intervention. This article discusses the leading behavioral treatment of insomnia, cognitive behavioral therapy for insomnia, and its ability to be tailored to an individual's specific ...
Elaine, Boland +3 more
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