Results 271 to 280 of about 4,218,282 (383)

A Comprehensive Oncological Biomarker Framework Guiding Precision Medicine. [PDF]

Biomolecules
Mokhtari RB, Sambi M, Shekari F, Satari K, Ghafoury R, Ashayeri N, Eversole P, Baluch N, Harless WW, Muscarella LA, Yeger H, Das B, Szewczuk MR, Chakraborty S.   +13 more
europepmc   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler, Aleksandra Maleska Maceski, Sofia Sandgren, Johanna Oechtering, Sabine Schaedelin, Lisa Hofer, Amar Zadic, Juan Francisco Vilchez Gomez, Lester Melie‐Garcia, Alessandro Cagol, Riccardo Galbusera, Sebastian Finkener, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D’Souza, Lars G. Hemkens, Tobias Derfuss, Özgür Yaldizli, Patrick Roth, Claudio Gobbi, David Brassat, Björn Tackenberg, Henrik Zetterberg, Tjalf Ziemssen, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Fredrik Piehl, Ludwig Kappos, Cristina Granziera, Ahmed Abdelhak, David Leppert, Eline A. J. Willemse, Pascal Benkert, Jens Kuhle, Swiss Multiple Sclerosis Cohort Study (SMSC)   +43 more
wiley   +1 more source

Precision Medicine in Orthobiologics: A Paradigm Shift in Regenerative Therapies. [PDF]

Bioengineering (Basel)
Navani A, Jeyaraman M, Jeyaraman N, Ramasubramanian S, Nallakumarasamy A, Azzini G, Lana JF.   +6 more
europepmc   +1 more source

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source

Artificial Intelligence and Network Medicine: Path to Precision Medicine. [PDF]

NEJM AI
Altucci L, Badimon L, Balligand JL, Baumbach J, Catapano AL, Cheng F, DeMeo D, Gupta R, Hacker M, Liu YY, Loscalzo J, Maniscalco S, Menche J, Menichetti G, Parini P, Schmidt HHHW, Zitnik M.   +16 more
europepmc   +1 more source

Dosingde novocombinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers

, 2016
Sariah Liu, Mina Nikanjam, Razelle Kurzrock   +2 more
openalex   +2 more sources

Pharmacokinetic Pharmacogenetic Prescribing Guidelines for Antidepressants: A Template for Psychiatric Precision Medicine [PDF]

, 2016
Malik Nassan, Wayne T. Nicholson, Michelle A. Elliott, Carolyn R. Rohrer Vitek, John L. Black, Mark A. Frye   +5 more
openalex   +1 more source

Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun, Alpay Özcan, Fuat Kaan Aras, Evrim Bozdemir, Sibel Uğur İşeri, Koray Kırımtay, Arzu Karabay, Murat Gültekin, Nihan Hande Akçakaya, Orkhan Mammadov, Gülay Kır, Dilek İnce Günal, Neşe Tuncer, Fatma Betül Özdilek, Banu Özen Barut, Ercan Köse, Hülya Apaydın, Asuman Ali, Sultan Çağırıcı, Pınar Topaloğlu, Alp Dinçer, Zuhal Yapıcı   +21 more
wiley   +1 more source

MRI: A Dynamic Tool in Precision Medicine. [PDF]

Chem Biomed Imaging
Huang Z, Ye D.
europepmc   +1 more source

Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine [PDF]

, 2016
Ruifang Sun, L. Jeffrey Medeiros, Ken H. Young   +2 more
openalex   +1 more source