Results 101 to 110 of about 128,608 (313)

Point-HRRP-Net: A Deep Fusion Framework via Bi-Directional Cross-Attention for Space Object Classification Using HRRP and Point Cloud

Remote Sensing
High-Resolution Range Profile (HRRP)-based space object classification is severely limited by aspect sensitivity. Inspired by the intrinsic complementarity between HRRP and LiDAR point clouds, this work investigates the feasibility and effectiveness of ...
Zhenou Zhao, Zhuoyi Yang, Haitao Zhang, Yanwei Wang, Kuo Meng   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Review of Research Progress in Microfluidic Bioseparation and Bioassay

Micromachines
With the rapid development of biotechnology, the importance of microfluidic bioseparation and bioassay in biomedicine, clinical diagnosis, and other fields has become increasingly prominent.
Heng Zhao, Yanyan Zhang, Dengxin Hua
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Equifertiles - the key to extend the supervised areas of ground based remote sensing systems

, 2004
Equifertiles (EQF) are areas of similar productivity within a field. EQFs can be derived either from yield data (inductive approach) or from soil fertility data closely related to crop productivity (deductive approach).
Lilienthal, Holger, Schnug, Ewald
core  

Nitrogen fertilizer recommendations based on precision sensing and Bayesian updating [PDF]

Methods are available to predict nitrogen needs of winter wheat based on plant sensing, but adoption rates by producers are low. Low adoption rates are likely due to economic feasibility.
Brorsen, B. Wade, McFadden, Brandon R.
core   +1 more source

Deep learning enabled robust wavefront sensing for active beam smoothing with a continuous phase modulator

High Power Laser Science and Engineering
In laser systems requiring a flat-top distribution of beam intensity, beam smoothing is a critical technology for enhancing laser energy deposition onto the focal spot.
Yamin Zheng, Yifan Zhang, Liquan Guo, Pei Li, Zichao Wang, Yongchen Zhuang, Shibing Lin, Qiao Xue, Deen Wang, Lei Huang   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Precision Nitrogen Fertilization Technology with Micro Grids

Sensor-based precision fertilizer technologies are being developed and researched by production scientists. One such technology uses normalized difference vegetation index (NDVI) reflectance measurements of growing winter wheat plants and a nitrogen ...
Raun, Bill, Biermacher, Jon T., Brorsen, B. Wade, Solie, John B., Epplin, Francis M.   +4 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source