Results 161 to 170 of about 6,451,122 (364)

Amplification‐Free, Sequencing‐Free, Detection of Viral RNAs with Variant Specification by Discrete Nanocounting

Advanced Functional Materials, EarlyView.
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang, Xi Zhao, Wan‐Mui Chan, Xianglin Ji, Linfeng Huang, Xi Xie, Wei Li, Wenjun Zhang, Kelvin Kai‐Wang To, Peng Shi   +9 more
wiley   +1 more source

PET Probes for Preclinical Imaging of GRPR-Positive Prostate Cancer: Comparative Preclinical Study of [⁶⁸Ga]Ga-NODAGA-AMBA and [⁴⁴Sc]Sc-NODAGA-AMBA. [PDF]

Int J Mol Sci, 2022
Kálmán-Szabó I, Szabó JP, Arató V, Dénes N, Opposits G, Jószai I, Kertész I, Képes Z, Fekete A, Szikra D, Hajdu I, Trencsényi G.   +11 more
europepmc   +1 more source

Preclinical Evaluation of ¹⁸F-JNJ41510417 as a Radioligand for PET Imaging of Phosphodiesterase-10A in the Brain [PDF]

, 2010
Sofie Celen, Michel Koole, Meri De Angelis, I. SANNEN, Satish K. Chitneni, Jesús Alcázar, Stefanie Dedeurwaerdere, Dieder Moechars, Mark E. Schmidt, Alfons Verbruggen, Xavier Langlois, Koen Van Laere, José Ignacio Andrés, Guy Bormans   +13 more
openalex   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Sex-Specific Adaptations in Alzheimer’s Disease and Ischemic Stroke: A Longitudinal Study in Male and Female APP_swe/PS1_dE9 Mice

Life
The long-term impact of stroke on Alzheimer’s disease (AD) progression, particularly regarding sex-specific differences, remains unknown. Using a longitudinal study design, we investigated transient middle cerebral artery occlusion in 3.5-month-old ...
Klara J. Lohkamp, Nienke Timmer, Gemma Solé Guardia, Justin Shenk, Vivienne Verweij, Bram Geenen, Pieter J. Dederen, Lieke Bakker, Cansu Egitimci, Rengin Yoldas, Minou Verhaeg, Josine Kothuis, Desirée Nieuwenhuis, Maximilian Wiesmann, Amanda J. Kiliaan   +14 more
doaj   +1 more source

Dynamic Micromechanical Characterization of 3D Printed Bone In Vitro Models Manufactured via Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This study presents a novel approach to designing and fabricating high‐porosity 3D‐printed scaffolds using a customized resin. Scaffold geometry, cellular interactions, and mechanical properties are analyzed to demonstrate these engineered bone models.
Sera Choi, Elizabeth Hunt, Edward A. Shangin, Zahra Bahranifard, Emma Nguyen, Caitlyn J. Collins, Abby R. Whittington   +6 more
wiley   +1 more source

Preclinical Water-Mediated Ultrasound Platform using Clinical FOV for Molecular Targeted Contrast-Enhanced Ultrasound [PDF]

arXiv
Background: This protocol introduces an ultrasound (US) configuration for whole-body 3D dynamic contrast-enhanced ultrasound (DCE-US) imaging in preclinical applications. The set-up relies on a clinical abdominal matrix US probe to enable mice imaging beyond current preclinical systems that are generally unable to capture whole-body volumetric and ...
arxiv  

Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging [PDF]

, 2011
Adelaide Greco, Marcello Mancini, Sara Gargiulo, Matteo Gramanzini, Pier Paolo Claudio, Arturo Brunetti, Marco Salvatore   +6 more
openalex   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

Development of PET Radioligands Targeting COX-2 for Colorectal Cancer Staging, a Review of in vitro and Preclinical Imaging Studies. [PDF]

Front Med (Lausanne), 2021
Dagallier C, Avry F, Touchefeu Y, Buron F, Routier S, Chérel M, Arlicot N.   +6 more
europepmc   +1 more source