Brain-Aware Readout Layers in GNNs: Advancing Alzheimer's early Detection and Neuroimaging [PDF]
arXivAlzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This study introduces a novel brain-aware readout layer (BA readout layer) for Graph Neural Networks (GNNs), designed to ...
arxiv
Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine
Advanced Functional Materials, EarlyView.Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang +5 more
wiley +1 more source
CD19-immunoPET for noninvasive visualization of CD19 expression in B-cell lymphoma patients
Biomarker ResearchCell- and antibody-based CD19-directed therapies have demonstrated great potential for treating B-cell non-Hodgkin lymphoma (B-NHL). However, all these approaches suffer from limited response rates and considerable toxicity.
Dominik Sonanini +17 more
doaj +1 more source
Longitudinal Preclinical Imaging Characterizes Extracellular Drug Accumulation After Radiation Therapy in the Healthy and Leukemic Bone Marrow Vascular Microenvironment. [PDF]
Int J Radiat Oncol Biol Phys, 2022 Brooks J +11 more
europepmc +1 more source
Preclinical Derivation and Imaging of Autologously Transplanted Canine Induced Pluripotent Stem Cells [PDF]
, 2011 Andrew S. Lee +23 more
openalex +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
Advanced Functional Materials, EarlyView.MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee +6 more
wiley +1 more source
Preclinical Evaluation of Raman Nanoparticle Biodistribution for their Potential Use in Clinical Endoscopy Imaging [PDF]
, 2011 Cristina Zavaleta +9 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Carboxyl‐functionalized graphene quantum dots (cGQDs) exhibit high singlet oxygen quantum yield due to strong spin–orbit coupling. cGQDs achieve minimum bactericidal concentration of only 0.4 µg mL−1 against S. aureus under low‐intensity illumination.
Muhammad Hassnain +10 more
wiley +1 more source
Optical imaging in vivo with a focus on paediatric disease: technical progress, current preclinical and clinical applications and future perspectives [PDF]
, 2011 Joanna Napp +2 more
openalex +1 more source
Developments in preclinical and clinical imaging
Journal of Orthopaedic Translation, 2014 Bruno J. Koller, Nicolas Vilayphiou
openaire +3 more sources