Results 131 to 140 of about 13,502,816 (309)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Subchronic toxicity of a drug based on D-cyphenothrin, pyriproxyfen and piperonyl butoxide

Российский паразитологический журнал
The purpose of the research is to study the effects of a combined drug based on D-cyphenothrin, pyriproxyfen and piperonyl butoxide on the body of rats with repeated dermal application in a subchronic experiment.Materials and methods. The drug subchronic
M. V. Arisov, D. S. Poselov, E. V. Poselova, A. A. Stepanov, T. S. Novik   +4 more
doaj   +1 more source

Preclinical Study [PDF]

, 2020
openaire   +1 more source

Nine preclinical studies out of 14 reported data on observed abscopal effect in the non-irradiated controlateral tumor.

, 2017
Nine preclinical studies out of 14 reported data on observed abscopal effect in the non-irradiated controlateral tumor.
Silvia Strolin (3769477), Lidia Strigari (51527), Gianluca Bossi (333041), Raffaella Marconi (3769480)   +3 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights

Antioxidants
Hydrogen-rich water (HRW) has shown neuroprotective effects in acute brain injury, but its role in chronic radiation-induced brain injury (RIBI) remains unclear. This study investigated the long-term efficacy of HRW in mitigating cognitive impairment and
Kai Xu, Huan Liu, Yinhui Wang, Yushan He, Mengya Liu, Haili Lu, Yuhao Wang, Piye Niu, Xiujun Qin   +8 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Preclinical Studies in Vascularized Composite Allotransplantation

Plastic and Reconstructive Surgery, Global Open, 2023
Andreea Grosu-Bularda, Dragos Zamfirescu, Florin-Vlad Hodea, Alexandru Stoian, Luana Lazarescu, Razvan Nicolae Teodoreanu, Ioan Lascar   +6 more
doaj   +1 more source

Development of HIV/AIDS vaccine based on Tat: preclinical and clinical studies.

, 2002
The results of preclinical and clinical studies using an HIV-1 Tat-based vaccines are ...
Belli R, Ensoli B., Mancini MG, Magnani M, Titti F, Vardas E, Buttò S, Sernicola L, Cafaro A, Lagaurdia E, Tripiciano A, Scoglio A, Nappi F, Colvin M, Fanales-Belasio E, Maggiorella MT, Macchia I, Michelini Z, Farcomeni S, Fanales Belasio E, Fiorelli V, Cara A, Ridolfi B, Caputo A, CAPUTO, ANTONELLA, Borsetti A, Negri DRM, Baroncelli S, Moretti S   +28 more
core  

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source