Results 191 to 200 of about 808,538 (334)

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Elucidating the Anticancer Mechanisms of Tetrahydroxycurcumin: A Comprehensive Review of Preclinical Studies. [PDF]

Food Sci Nutr
Shahbaz M, Momal U, Mohamed HM, Perween A, Naeem H, Imran M, Hussain M, Mohamed GA, Ibrahim SRM, Yehuala TF, Alsagaby SA, Al Abdulmonem W, Abdelgawad MA, Mostafa EM, Selim S.   +14 more
europepmc   +1 more source

Referee report. For: Feasibility and guidelines for the use of an injectable fiducial marker (BioXmark®) to improve target delineation in preclinical radiotherapy studies using mouse models. [version 1; peer review: 1 approved with reservations]

, 2023
Emma Biglin
openalex   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Prospects for clinical translation of histotripsy in liver applications: a systematic review based on preclinical studies. [PDF]

Quant Imaging Med Surg
Yu Y, Yan X, Gui Y, Lv K, Jiang Y.
europepmc   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Cannabis-Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies. [PDF]

Trop Med Int Health
de Mendonça Lima T, de Sena LWP, de Sousa ACC, de Freitas GRM, Rotta I, Visacri MB.   +5 more
europepmc   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Dihydroquercetin in Weight Control: Systematic Review and Meta-Analysis of Preclinical Studies. [PDF]

Pharmaceuticals (Basel)
Terekhov RP, Svotin AA, Pankov DI, Korochkina MD, Krivosheeva EA, Krivozubova EV, Bergel KI, Selivanova IA.   +7 more
europepmc   +1 more source

Advanced MRI Center: a 3 Tesla Magnetic Resonance system for preclinical, translational and clinical imaging studies

, 2020
Letterio S. Politi, Shaokuan Zheng, Matthew J. Gounis   +2 more
openalex   +1 more source