Results 191 to 200 of about 814,690 (301)

Impact of Antenatal Corticosteroids on Brain Function and Underlying Mechanisms in Preclinical Studies: Protocol for a Systematic Review.

JMIR Res Protoc
Herselman MF, Hislop T, McBride SD, Lock MC, Morrison JL, Gatford KL.   +5 more
europepmc   +1 more source

A systematic review and meta-analysis of astaxanthin efficacy in male infertility: evidence from clinical and preclinical studies. [PDF]

Sci Rep
Dehpahni MF, Hoolari BB, Amidi F.
europepmc   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

Modulatory role of Akkermansia muciniphila in cancer pathophysiology: a systematic review and meta-analysis of preclinical studies. [PDF]

Gut Pathog
Khalili L, Park G, Nagpal R, Salazar G.
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Protective effects of salvianolic acid A on ischemic stroke: A meta-analysis of preclinical studies. [PDF]

Front Pharmacol
Liu A, Li W, Zhang H, Sun K, Xiao Y, Wan J, Li P, Wang Y, Hu S, Li Y, Bai Y.   +10 more
europepmc   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Effects of ayahuasca in preclinical studies with animals: a systematic review. [PDF]

Braz J Med Biol Res
Walsh-Monteiro A, Morato S, Uribe FAR, Gouveia A, Pedroso JS.   +4 more
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Pharmacological and Genetic Targeting of Inflammatory Chemokine Receptors CCR1, CCR2, and CCR5 in Atherosclerosis: A Systematic Review and Meta-Analysis of Preclinical Studies. [PDF]

J Am Heart Assoc
Shoaran M, Caiazzo E, Morsy MI, Gurgone D, MacRitchie N, Bruzzese D, Ialenti A, Guzik TJ, Graham GJ, Maffia P.   +9 more
europepmc   +1 more source