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Preclinical studies of dendrimer prodrugs
Expert Opinion on Drug Metabolism & Toxicology, 2015Dendrimers are synthetic macromolecules with well-defined structures bearing a wide variety of functional groups on their periphery. These groups can be used to conjugate bioactive molecules such as drugs, ligands and imaging agents. Dendrimer prodrugs can be used to improve the water solubility and pharmacokinetic properties of the corresponding free ...
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Preclinical Studies in Osteoarthritis
1999We are entering into a new era as a myriad of new approaches to the treatment of osteoarthritis (OA) is under development. While the traditional therapies have been directed at symptoms, many of the new approaches are directed at structure (disease) modification.
M. Sisay, R. D. Altman
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